Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680814 | 0.95 | BTK (0.37) | BTKMAPK8SYKMAPK11MAPK14 | |
| SCHEMBL1680407 | 0.89 | MAPK8 (0.40) | MAPK8ALDH1A1L3MBTL1TDP1GAA | |
| SCHEMBL1681212 | 0.82 | BTK (0.35) | BTKMAPK8 | |
| SCHEMBL1680840 | 0.82 | KLKB1 (0.39) | MAPK8ALDH1A1L3MBTL1TDP1GAA | |
| SCHEMBL1680856 | 0.81 | ALDH1A1 (0.40) | MAPK8ALDH1A1L3MBTL1TDP1GAA | |
| SCHEMBL1681018 | 0.80 | MAPK8 (0.42) | MAPK8ALDH1A1L3MBTL1GAAHPGD | |
| SCHEMBL1681063 | 0.80 | CCNA2 (0.36) | MAPK8ALDH1A1L3MBTL1TDP1GAA | |
| SCHEMBL1680984 | 0.80 | MAPK8 (0.35) | BTKMAPK8ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL1680854 | 0.80 | MAPK1 (0.39) | BTKMAPK8MAPK1 | |
| SCHEMBL1680874 | 0.80 | ALDH1A1 (0.48) | MAPK8ALDH1A1L3MBTL1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195999-A1 | NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND | NAKAMOTO KAZUTAKA | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195999-A1 | NOVEL ANTIFUNGAL AGENT CONTAINING HETEROCYCLIC COMPOUND | ERG28, CYP51A1, XPO1 | BTK 2496/4885MAPK8 2211/4885ALDH1A1 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.