Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | USP8 | P40818 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239557 | 0.79 | USP8 (0.44) | L3MBTL1MAPK1MAPTKMT2AALDH1A1 | |
| SCHEMBL31280272 | 0.79 | GAA (0.38) | L3MBTL1MAPK1MAPTKMT2AALDH1A1 | |
| SCHEMBL29341106 | 0.79 | GAA (0.38) | L3MBTL1MAPK1MAPTKMT2AALDH1A1 | |
| SCHEMBL30630762 | 0.78 | PLCG1 (0.36) | L3MBTL1MAPK1KMT2AALDH1A1KDM4E | |
| SCHEMBL2238931 | 0.78 | PLCG1 (0.36) | L3MBTL1MAPK1MAPTKMT2AALDH1A1 | |
| SCHEMBL23218431 | 0.78 | PLCG1 (0.36) | L3MBTL1MAPK1MAPTKMT2AALDH1A1 | |
| SCHEMBL30527595 | 0.78 | PLCG1 (0.36) | L3MBTL1MAPK1MAPTKMT2AALDH1A1 | |
| SCHEMBL29852563 | 0.78 | PLCG1 (0.36) | L3MBTL1MAPK1MAPTKMT2AALDH1A1 | |
| SCHEMBL29539340 | 0.78 | PLA2G2A (0.37) | MAPK1ALDH1A1KDM4EPLCG1USP8 | |
| SCHEMBL2671146 | 0.75 | ALDH1A1 (0.40) | L3MBTL1MAPK1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003799-B2 | For agriculture | BAYER SAS (FR) | 2011-08-23 | — | — | US | disclosed |
| US-7560565-B2 | Method for preparing derivatives of 3-hydroxypicolinic acid | BAYER CROPSCIENCE SA (FR) | 2009-07-14 | — | — | US | disclosed |
| EP-1244627-B1 | PICOLINIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-09-20 | — | — | EP | disclosed |
| EP-1248771-B1 | METHOD FOR PREPARING HYDROXYPICOLINIC ACID DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2006-05-03 | — | — | EP | disclosed |
| US-20060040995-A1 | Method for preparing hydroxypicolinic scid derivatives | AVENTIS CROPSCIENCE, S.A. (FR) | 2006-02-23 | — | — | US | disclosed |
| US-20030191113-A1 | Picolinic acid derivatives and their use as fungicides | BAYER SAS (FR) | 2003-10-09 | — | — | US | disclosed |
| EP-1248771-A1 | METHOD FOR PREPARING HYDROXYPICOLINIC ACID DERIVATIVES | Bayer CropScience S.A. (FR) | 2002-10-16 | — | — | EP | disclosed |
| EP-1244627-A1 | PICOLINIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001049666-A1 | PICOLINIC ACID DERIVATIVES AND THEIR USE AS FUNGICIDES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-07-12 | — | — | WO | disclosed |
| WO-2001049667-A1 | METHOD FOR PREPARING HYDROXYPICOLINIC ACID DERIVATIVES | AVENTIS CROPSCIENCE S.A. (FR) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040995-A1 | Method for preparing hydroxypicolinic scid derivatives | CYP2F1, CYP21A2, CYP26B1 | L3MBTL1 4066/4885MAPK1 4340/4885MAPT 4871/4885 |
| US-20030191113-A1 | Picolinic acid derivatives and their use as fungicides | PTPRG, CNPY2, CYP4X1 | L3MBTL1 3632/4885MAPK1 2821/4885MAPT 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.