Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.32 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28021349 | 0.89 | LMNA (0.31) | LMNA | |
| SCHEMBL4876333 | 0.80 | — | — | |
| SCHEMBL15757857 | 0.80 | — | — | |
| SCHEMBL11030067 | 0.76 | — | — | |
| SCHEMBL8934264 | 0.76 | — | — | |
| SCHEMBL9388506 | 0.72 | — | — | |
| SCHEMBL4939347 | 0.72 | — | — | |
| SCHEMBL183518 | 0.72 | — | — | |
| SCHEMBL3823579 | 0.72 | NFKB1 (0.30) | NFKB1 | |
| Methacrylic Acid SCHEMBL28984392 | 0.72 | TSHR (0.37) | SLC22A6TSHRTHRBKMT2AHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2559534-B1 | Composition and method for casting manufacturing | RAYTHEON TECH CORP (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-2539091-B1 | CASTING CORE FOR TURBINE ENGINE COMPONENTS AND METHOD OF MAKING THE SAME | SIEMENS ENERGY INC (US) | 2020-10-21 | — | — | EP | disclosed |
| EP-2559533-B1 | Casting | UNITED TECHNOLOGIES CORP (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-3036055-B1 | TURBINE COMPONENT CASTING CORE WITH HIGH RESOLUTION REGION | SIEMENS ENERGY INC (US) | 2019-07-03 | — | — | EP | disclosed |
| US-10207315-B2 | Systems, devices, and/or methods for manufacturing castings | UNITED TECHNOLOGIES CORPORATION (US) | 2019-02-19 | — | — | US | disclosed |
| EP-3036055-A1 | TURBINE COMPONENT CASTING CORE WITH HIGH RESOLUTION REGION | Siemens Energy, Inc. (US) | 2016-06-29 | — | — | EP | disclosed |
| US-9315663-B2 | Systems, devices, and/or methods for manufacturing castings | MIKRO SYSTEMS, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20160082502-A1 | Systems, Devices, and/or Methods for Manufacturing Castings | RTX CORPORATION | 2016-03-24 | — | — | US | disclosed |
| US-9206309-B2 | Systems, devices, and/or methods for manufacturing castings | MIKRO SYSTEMS, INC. (US) | 2015-12-08 | — | — | US | disclosed |
| US-8813812-B2 | Turbine component casting core with high resolution region | SIEMENS ENERGY, INC. (US) | 2014-08-26 | — | — | US | disclosed |
| EP-2559533-A2 | Systems, devices, and/or methods for manufacturing castings | Mikro Systems Inc. (US) | 2013-02-20 | — | — | EP | disclosed |
| EP-2559535-A2 | Systems, devices, and/or methods for manufacturing castings | Mikro Systems Inc. (US) | 2013-02-20 | — | — | EP | disclosed |
| EP-2559534-A2 | Systems, devices, and/or methods for manufacturing castings | Mikro Systems Inc. (US) | 2013-02-20 | — | — | EP | disclosed |
| EP-2539091-A1 | CASTING CORE FOR TURBINE ENGINE COMPONENTS AND METHOD OF MAKING THE SAME | Siemens Energy, Inc. (US) | 2013-01-02 | — | — | EP | disclosed |
| EP-2362822-A2 | SYSTEMS, DEVICES, AND/OR METHODS FOR MANUFACTURING CASTINGS | Mikro Systems Inc. (US) | 2011-09-07 | — | — | EP | disclosed |
| WO-2011106131-A1 | CASTING CORE FOR TURBINE ENGINE COMPONENTS AND METHOD OF MAKING THE SAME | SIEMENS ENERGY, INC. (US) | 2011-09-01 | — | — | WO | disclosed |
| US-20110204205-A1 | CASTING CORE FOR TURBINE ENGINE COMPONENTS AND METHOD OF MAKING THE SAME | ENERGY, UNITED STATE DEPARTMENT OF | 2011-08-25 | — | — | US | disclosed |
| US-20110189440-A1 | Systems, Devices, and/or Methods for Manufacturing Castings | MIKRO SYSTEMS, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| WO-2010036801-A2 | SYSTEMS, DEVICES, AND/OR METHODS FOR MANUFACTURING CASTINGS | APPLEBY MICHAEL (US) | 2010-04-01 | — | — | WO | disclosed |
| US-3957715-A | SILICONE RESIN | HOWMET CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |