Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 18/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22371382 | 0.92 | RIPK1 (0.55) | RIPK1PIK3CA | |
| SCHEMBL30468375 | 0.92 | RIPK1 (0.55) | RIPK1PIK3CA | |
| SCHEMBL30468372 | 0.85 | RIPK1 (0.58) | RIPK1 | |
| SCHEMBL22371197 | 0.85 | RIPK1 (0.58) | RIPK1 | |
| SCHEMBL22371359 | 0.83 | RIPK1 (0.58) | RIPK1 | |
| Lithium Ion SCHEMBL29849729 | 0.83 | RIPK1 (0.56) | RIPK1 | |
| SCHEMBL22371320 | 0.82 | RIPK1 (0.59) | RIPK1 | |
| Lithium Ion SCHEMBL29849584 | 0.80 | RIPK1 (0.57) | RIPK1 | |
| SCHEMBL3150310 | 0.77 | PIK3CA (0.68) | RIPK1PIK3CA | |
| SCHEMBL24782368 | 0.76 | CSNK1D (0.45) | RIPK1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704118-A1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2020-09-09 | — | — | EP | disclosed |