⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11132397 | 0.79 | NPSR1 (0.30) | — | |
| SCHEMBL7941111 | 0.76 | — | — | |
| SCHEMBL10359878 | 0.76 | LMNA (0.32) | — | |
| SCHEMBL27550343 | 0.74 | — | — | |
| SCHEMBL27690657 | 0.73 | NPSR1 (0.30) | — | |
| SCHEMBL2289336 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL29013293 | 0.71 | PTPN1 (0.38) | — | |
| SCHEMBL25434480 | 0.70 | CES1 (0.34) | — | |
| SCHEMBL25436038 | 0.69 | — | — | |
| SCHEMBL29141575 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190467-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2011-08-04 | — | — | US | disclosed |
| US-20090276042-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
| EP-2021399-A1 | BIOLOGICAL POLYSILOXANES | VISION CRC LIMITED (AU) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007128051-A1 | BIOLOGICAL POLYSILOXANES | VISION CRC LIMITED (AU) | 2007-11-15 | — | — | WO | disclosed |