SCHEMBL22399174

SCHEMBL22399174

CC(C)(CN1C(=O)C=CC1=O)CN1C(=O)C=CC1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.52
BLM P54132 3/20 0.52
ALDH1A1 P00352 3/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
GMNN O75496 1/20 0.52
THPO P40225 1/20 0.52
PMP22 Q01453 1/20 0.52
WRN Q14191 2/20 0.50
FAAH O00519 4/20 0.46
HPGD P15428 2/20 0.44
HSP90AA1 P07900 1/20 0.44
TLR9 Q9NR96 1/20 0.44
TP53 P04637 1/20 0.44
PKM P14618 1/20 0.44
XBP1 P17861 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18511472 0.88 MGLL (0.46) MGLLBLMALDH1A1LMNAMAPT
SCHEMBL16552283 0.88 MGLL (0.52) MGLLBLMALDH1A1LMNAMAPT
SCHEMBL17924912 0.86 MGLL (0.44) MGLLBLMALDH1A1LMNAMAPT
SCHEMBL23900909 0.86 MGLL (0.44) MGLLBLMALDH1A1LMNAMAPT
SCHEMBL409863 0.84 MGLL (0.52) MGLLBLMALDH1A1LMNAMAPT
SCHEMBL13355241 0.83 MGLL (0.41) MGLLBLMALDH1A1LMNAMAPT
SCHEMBL15269449 0.83 CYP2C19 (0.47) MGLLBLMALDH1A1LMNAMAPT
SCHEMBL17924888 0.83 MGLL (0.41) MGLLBLMALDH1A1LMNAMAPT
SCHEMBL23900539 0.83 MGLL (0.46) MGLLBLMALDH1A1LMNAMAPT
SCHEMBL17924948 0.80 MGLL (0.48) MGLLBLMALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3632941-B1 RESIN COMPOSITION CUBICURE GMBH (AT) 2023-08-23 EP claimed
EP-3632941-B1 RESIN COMPOSITION CUBICURE GMBH (AT) 2023-08-23 EP disclosed
US-20210395420-A1 RESIN COMPOSITION CUBICURE GMBH (AT) 2021-12-23 US disclosed
US-10768539-B2 Electrophotographic photosensitive member, production method therefor, process cartridge, and electrophotographic image-forming apparatus CANON KABUSHIKI KAISHA (JP) 2020-09-08 US disclosed