Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22399174 | 0.84 | MGLL (0.52) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL23900909 | 0.81 | MGLL (0.44) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL17924948 | 0.80 | MGLL (0.48) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL22399175 | 0.78 | MGLL (0.46) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL16552283 | 0.78 | MGLL (0.52) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL18511472 | 0.78 | MGLL (0.46) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL10437675 | 0.77 | MGLL (0.44) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL17924912 | 0.77 | MGLL (0.44) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL10107222 | 0.77 | MGLL (0.44) | MGLLALDH1A1BLMLMNAMAPT | |
| SCHEMBL16543625 | 0.75 | MGLL (0.54) | MGLLALDH1A1BLMLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933715-A | N-substituted maleic imide preservative for aqueous dispersions of polymers derived from α, β-ethylenically unsaturated monomers | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | claimed |
| US-20240018298-A1 | OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS | ExxonMobil Product Solutions Company | 2024-01-18 | — | — | US | disclosed |
| US-11732259-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-11732259-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-11530407-B2 | Short interfering nucleic acid (siNA) compositions | SIRNA THERAPEUTICS, INC. (US) | 2022-12-20 | — | — | US | disclosed |
| US-20220127491-A1 | COATING COMPOSITIONS | ExxonMobil Product Solutions Company | 2022-04-28 | — | — | US | disclosed |
| WO-2022036044-A1 | OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS | MATERIA, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| US-11225662-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2022-01-18 | — | — | US | disclosed |
| US-11071749-B2 | Oligonucleotide analogues targeting human LMNA | SAREPTA THERAPEUTICS, INC. (US) | 2021-07-27 | — | — | US | disclosed |
| US-20210139896-A1 | Peptide Oligonucleotide Conjugates | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2021-05-13 | — | — | US | disclosed |
| US-20130223803-A1 | RESIN COMPOSITION FOR FORMATION OF OPTICAL WAVEGUIDE, RESIN FILM FOR FORMATION OF OPTICAL WAVEGUIDE WHICH COMPRISES THE RESIN COMPOSITION, AND OPTICAL WAVEGUIDE PRODUCED USING THE RESIN COMPOSITION OR THE RESIN FILM | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2013-08-29 | — | — | US | disclosed |
| US-20130224227-A1 | NOVEL CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS | BYONDIS B.V. (NL) | 2013-08-29 | — | — | US | disclosed |
| US-20130183270-A1 | Orally Bioavailable Lipid-Based Constructs | SDG, INC. (US) | 2013-07-18 | — | — | US | disclosed |
| US-20120289457-A1 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | AVI BIOPHARMA, INC. (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120065169-A1 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2012-03-15 | — | — | US | disclosed |
| US-20120041194-A1 | NITROGEN AND SULFUR-CONTAINING HETROCYCLE DERIVATIVES | TRIAD MULTITECH PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| US-20110269953-A1 | Nitrogen and Sulfur-Containing Heterocycle Derivatives | ARMILLI MURTY N | 2011-11-03 | — | — | US | disclosed |
| WO-2010118306-A1 | PHOTO-ACTIVATED ATTACHMENT OF CHOLESTEROL TO POLYURETHANE SURFACES FOR ADHESION OF ENDOTHELIAL CELLS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20100080773-A1 | Orally Bioavailable Lipid-Based Constructs | SDG, INC. | 2010-04-01 | — | — | US | disclosed |
| US-20070248988-A1 | Binding molecules and methods of use thereof | BIOGEN MA INC. | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065169-A1 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS | NSUN2, UPF1, RTCB | MGLL 4774/4885ALDH1A1 2803/4885BLM 1342/4885 |
| US-20100080773-A1 | Orally Bioavailable Lipid-Based Constructs | FABP2, FABP1, LIPC | MGLL 1067/4885ALDH1A1 3404/4885BLM 3123/4885 |
| US-11071749-B2 | Oligonucleotide analogues targeting human LMNA | LMNB2, LMNA, LMNB1 | MGLL 2684/4885ALDH1A1 4394/4885BLM 1288/4885 |
| US-20130183270-A1 | Orally Bioavailable Lipid-Based Constructs | FABP2, FABP1, LIPC | MGLL 1067/4885ALDH1A1 3404/4885BLM 3123/4885 |
| US-20120041194-A1 | NITROGEN AND SULFUR-CONTAINING HETROCYCLE DERIVATIVES | HRH4, HNMT, TST | MGLL 3517/4885ALDH1A1 3477/4885BLM 4455/4885 |
| US-20210139896-A1 | Peptide Oligonucleotide Conjugates | SNRPE, SMN1; SMN2, UPF1 | MGLL 4692/4885ALDH1A1 3700/4885BLM 1631/4885 |
| US-20070248988-A1 | Binding molecules and methods of use thereof | SHBG, CACYBP, CD2BP2 | MGLL 3016/4885ALDH1A1 2851/4885BLM 770/4885 |
| US-20120289457-A1 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | SNRPE, SMN1; SMN2, UPF1 | MGLL 4692/4885ALDH1A1 3700/4885BLM 1631/4885 |
| US-20110269953-A1 | Nitrogen and Sulfur-Containing Heterocycle Derivatives | TST, HNMT, HRH4 | MGLL 4154/4885ALDH1A1 2899/4885BLM 4082/4885 |
| US-11225662-B2 | Peptide oligonucleotide conjugates | SNRPE, SMN1; SMN2, UPF1 | MGLL 4692/4885ALDH1A1 3700/4885BLM 1631/4885 |
| US-11732259-B2 | Peptide oligonucleotide conjugates | SNRPE, SMN1; SMN2, UPF1 | MGLL 4692/4885ALDH1A1 3700/4885BLM 1631/4885 |
| US-20130224227-A1 | NOVEL CONJUGATES OF CC-1065 ANALOGS AND BIFUNCTIONAL LINKERS | PCNA, DCLRE1A, CDC5L | MGLL 4610/4885ALDH1A1 2514/4885BLM 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.