Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18520816 | 0.73 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL24499701 | 0.70 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL22547338 | 0.69 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL22326777 | 0.69 | ALDH1A1 (0.39) | ALDH1A1CYP1A2 | |
| SCHEMBL22349704 | 0.69 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL22399904 | 0.67 | ALDH1A1 (0.37) | ALDH1A1CYP1A2 | |
| SCHEMBL22349659 | 0.62 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL29663136 | 0.62 | ACVR1 (0.42) | ALDH1A1 | |
| SCHEMBL22797271 | 0.60 | PDE4A (0.33) | ALDH1A1 | |
| SCHEMBL23228166 | 0.57 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766919-B2 | Cyclic di-nucleotide compounds as sting agonists | MERCK SHARP & DOHME CORP. (US) | 2020-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766919-B2 | Cyclic di-nucleotide compounds as sting agonists | STING1, CGAS, IFNAR1 | ALDH1A1 4183/4885CYP1A2 1485/4885CYP2D6 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.