Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.62 |
| ▸ | AHCY | P23526 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970970 | 0.86 | YTHDC1 (0.66) | YTHDC1AHCYADORA3ADORA1PDE4A | |
| SCHEMBL23771392 | 0.79 | YTHDC1 (0.66) | YTHDC1AHCYADORA3ADORA1PDE4A | |
| SCHEMBL763699 | 0.77 | YTHDC1 (1.00) | YTHDC1ADORA3ADORA1PDE4APDE4B | |
| SCHEMBL22399264 | 0.77 | ADORA2A (0.56) | AHCYADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL18521272 | 0.75 | ADORA2A (0.34) | YTHDC1AHCYADORA1ADORA2AADORA2B | |
| SCHEMBL21127807 | 0.75 | ADORA2A (0.34) | YTHDC1AHCYADORA1ADORA2AADORA2B | |
| SCHEMBL22326706 | 0.75 | FDPS (0.41) | YTHDC1ADORA1ADORA2A | |
| SCHEMBL20041716 | 0.75 | YTHDC1 (0.66) | YTHDC1AHCYADORA3ADORA1PDE4A | |
| SCHEMBL28252117 | 0.75 | YTHDC1 (0.66) | YTHDC1AHCYADORA3ADORA1PDE4A | |
| SCHEMBL28251676 | 0.75 | YTHDC1 (0.66) | YTHDC1AHCYADORA3ADORA1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766919-B2 | Cyclic di-nucleotide compounds as sting agonists | MERCK SHARP & DOHME CORP. (US) | 2020-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766919-B2 | Cyclic di-nucleotide compounds as sting agonists | STING1, CGAS, IFNAR1 | YTHDC1 985/4885AHCY 4788/4885ADORA3 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.