Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | SDCBP | O00560 | 1/20 | 0.42 |
| ▸ | SDC2 | P34741 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18664406 | 0.86 | BRD4 (0.48) | NAMPTL3MBTL1HDAC1 | |
| SCHEMBL20497328 | 0.80 | CYP1A2 (0.41) | TDP1HDAC1AKT1HDAC6LMNA | |
| SCHEMBL3180689 | 0.79 | L3MBTL1 (0.61) | NAMPTL3MBTL1MAPTTDP1HDAC1 | |
| SCHEMBL24088159 | 0.78 | L3MBTL1 (0.50) | NAMPTL3MBTL1MAPTTDP1HDAC1 | |
| SCHEMBL30473404 | 0.77 | KDM4E (0.47) | NAMPTL3MBTL1MAPTTDP1NPSR1 | |
| SCHEMBL18664517 | 0.76 | L3MBTL1 (0.51) | NAMPTL3MBTL1MAPTTDP1HDAC1 | |
| SCHEMBL506891 | 0.76 | CYP17A1 (0.61) | NAMPTL3MBTL1HDAC1GAASDCBP | |
| SCHEMBL2567630 | 0.76 | HDAC1 (0.57) | NAMPTL3MBTL1MAPTTDP1HDAC1 | |
| SCHEMBL1691047 | 0.76 | HDAC1 (0.67) | NAMPTL3MBTL1HDAC1GAASDCBP | |
| SCHEMBL17279959 | 0.75 | PRKD1 (0.56) | NAMPTL3MBTL1MAPTHDAC1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766890-B2 | Hepatitis B core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2020-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766890-B2 | Hepatitis B core protein modulators | HAVCR2, FABP1, MAVS | NAMPT 1790/4885L3MBTL1 1920/4885MAPT 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.