Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Urea. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL28478547 | 0.94 | LMNA (0.86) | — | |
| Urea SCHEMBL7040620 | 0.88 | — | — | |
| Urea SCHEMBL225908 | 0.88 | — | — | |
| Urea SCHEMBL6361905 | 0.88 | — | — | |
| Urea SCHEMBL11590334 | 0.88 | — | — | |
| Urea SCHEMBL23779965 | 0.88 | — | — | |
| Urea SCHEMBL10948406 | 0.88 | — | — | |
| Urea SCHEMBL11594201 | 0.88 | — | — | |
| Urea SCHEMBL10413304 | 0.88 | — | — | |
| Urea SCHEMBL30474846 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117378539-A | Hatching method for fertilized eggs of litopenaeus vannamei | 海南海兴农海洋生物科技有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-108813428-B | Sturgeon fish sausage making method and determination method based on F value superposition sterilization | ZHEJIANG GONGSHANG UNIVERSITY (CN) | 2021-06-22 | — | — | CN | claimed |
| EP-2536301-B1 | ORAL SMOKELESS TOBACCO PRODUCTS AND ORAL SMOKELESS NON-TOBACCO SNUFF PRODUCTS COMPRISING CARBAMIDE OR CARBAMIDE SALTS | SWEDISH MATCH NORTH EUROPE AB (SE) | 2020-04-01 | — | — | EP | claimed |
| CN-108813428-A | Sturgeon fish intestines production method and measuring method based on the superposition sterilization of F value | 浙江工商大学 | 2018-11-16 | — | — | CN | claimed |
| US-20130053603-A1 | ORAL SMOKELESS TOBACCO PRODUCTS AND ORAL SMOKELESS NON-TOBACCO SNUFF PRODUCTS COMPRISING CARBAMIDE OR CARBAMIDE SALTS | SWEDISH MATCH NORTH EUROPE AB (SE) | 2013-02-28 | — | — | US | claimed |
| EP-2536301-A1 | ORAL SMOKELESS TOBACCO PRODUCTS AND ORAL SMOKELESS NON-TOBACCO SNUFF PRODUCTS COMPRISING CARBAMIDE OR CARBAMIDE SALTS. | Swedish Match North Europe AB (SE) | 2012-12-26 | — | — | EP | claimed |
| WO-2011102788-A1 | ORAL SMOKELESS TOBACCO PRODUCTS AND ORAL SMOKELESS NON-TOBACCO SNUFF PRODUCTS COMPRISING CARBAMIDE OR CARBAMIDE SALTS. | SWEDISH MATCH NORTH EUROPE AB (SE) | 2011-08-25 | — | — | WO | claimed |
| CN-117378539-A | Hatching method for fertilized eggs of litopenaeus vannamei | 海南海兴农海洋生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117327959-A | Titanium modified molybdenum diselenide nanowire material, preparation method and application thereof, and self-lubricating block preparation method | 镇江市高等专科学校 | 2024-01-02 | — | — | CN | disclosed |
| CN-114532261-B | Semi-viscous fish egg debonding agent and application thereof in artificial propagation of sinocyclocheilus grahami | 西双版纳云博水产养殖开发有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-114532261-A | Semi-viscous fish egg debonder and application thereof in artificial propagation of sinocyclocheilus grahami | 西双版纳云博水产养殖开发有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108813428-B | Sturgeon fish sausage making method and determination method based on F value superposition sterilization | ZHEJIANG GONGSHANG UNIVERSITY (CN) | 2021-06-22 | — | — | CN | disclosed |
| EP-2536301-B1 | ORAL SMOKELESS TOBACCO PRODUCTS AND ORAL SMOKELESS NON-TOBACCO SNUFF PRODUCTS COMPRISING CARBAMIDE OR CARBAMIDE SALTS | SWEDISH MATCH NORTH EUROPE AB (SE) | 2020-04-01 | — | — | EP | disclosed |
| WO-2011102788-A1 | ORAL SMOKELESS TOBACCO PRODUCTS AND ORAL SMOKELESS NON-TOBACCO SNUFF PRODUCTS COMPRISING CARBAMIDE OR CARBAMIDE SALTS. | SWEDISH MATCH NORTH EUROPE AB (SE) | 2011-08-25 | — | — | WO | disclosed |
| CN-101541345-A | Stabilized antibody formulations and uses thereof | MEDIMMUNE INC (US) | 2009-09-23 | — | — | CN | disclosed |
| US-6719986-B1 | FERMENTED BY MICROORGANISMS; SKIN DISORDERS; AGING AND WRINKLE RESISTANCE | ESPARMA GMBH (DE) | 2004-04-13 | — | — | US | disclosed |
| CN-1031801-A | The human protein preparations of stabilisation | BOEHRINGER MANNHEIM GMBH (DE) | 1989-03-22 | — | — | CN | disclosed |
| CN-87102556-A | Chlorination technology of permanently effective phosphorous improves and wastewater treatment | — | 1988-10-12 | — | — | CN | disclosed |
| CN-87102556-A | Chlorination technology of permanently effective phosphorous improves and wastewater treatment | — | 1988-10-12 | — | — | CN | disclosed |
| US-4656249-A | SYNTHETIC PORCINE HORMOE AND ANALOGS; REDUCTION OF S-SULFONATED CHAINS AND A B; PRECIPITATION WITH ACETONE; AND OXIDATION AND RECOMBINING IN THE PRESENCE OF SODIUM CHLORIDE | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 1987-04-07 | — | — | US | disclosed |