SCHEMBL2240270

SCHEMBL2240270

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nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197824 0.92 TSHR (0.33)
Hydrogen Sulfide SCHEMBL28090943 0.92 TSHR (0.33)
Lithium Ion SCHEMBL2504315 0.88 TSHR (0.31)
Fluoride Ion SCHEMBL1260645 0.88 TSHR (0.31)
Hydrochloric Acid SCHEMBL20896 0.88 TSHR (0.31)
SCHEMBL596385 0.88 TSHR (0.31)
Iodide SCHEMBL2796494 0.88 TSHR (0.31)
Fluoride Ion SCHEMBL33106 0.88 TSHR (0.31)
SCHEMBL5327324 0.88 TSHR (0.31)
SCHEMBL2504316 0.88 TSHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7982052-B2 Process for the preparation of stable nitroxyl radicals POLIMERI EUROPA S.P.A. (IT) 2011-07-19 US disclosed
US-20100240909-A1 PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS POLIMERI EUROPA S.P.A. (IT) 2010-09-23 US disclosed
EP-1984335-B1 IMPROVED PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS POLIMERI EUROPA SPA (IT) 2009-08-19 EP disclosed
EP-1984335-A1 IMPROVED PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS Polimeri Europa S.p.A. (IT) 2008-10-29 EP disclosed
WO-2007093452-A1 IMPROVED PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS POLIMERI EUROPA S.P.A. (IT) 2007-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240909-A1 PROCESS FOR THE PREPARATION OF STABLE NITROXYL RADICALS PPOX, TET1, PBRM1 BBOX1 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.