Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4846755 | 0.83 | MMP3 (0.65) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL3849333 | 0.82 | MMP2 (0.59) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL4408915 | 0.82 | HDAC1 (0.66) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL1274377 | 0.82 | HDAC1 (0.66) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL6518366 | 0.81 | HDAC1 (0.50) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL5157671 | 0.80 | PPARA (0.53) | ALDH1A1TDP1KDM4EMEN1KMT2A | |
| SCHEMBL5706662 | 0.79 | TDP1 (0.39) | HDAC1HDAC2MAPTTDP1KDM4E | |
| SCHEMBL12348085 | 0.79 | TSHR (0.47) | MMP3HDAC1HDAC2MMP2MGLL | |
| SCHEMBL8939351 | 0.79 | MMP2 (0.67) | MMP3HDAC1HDAC2MMP2MAPT | |
| SCHEMBL29322190 | 0.78 | POLB (0.50) | MMP3HDAC1HDAC2MMP2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989037-B2 | A layer of discotic liquid-crystal and an anisotropic fluoropolymer of acrylic esters, e.g., 4-((4-nitrilophenoxy)butyl acrylate /2-(perfluorhexyl)ethyl acrylate copolymer; providing stability/optical compensation; no defects from optical fluctuation or alignment failure; controlling the tilt angle | FUJIFILM CORPORATION (JP) | 2011-08-02 | — | — | US | disclosed |
| US-20080090027-A1 | Composition, retardation plate, and liquid-crystal display device | FUJIFILM CORPORATION (JP) | 2008-04-17 | — | — | US | disclosed |