Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 3/20 | 0.46 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.46 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.41 |
| ▸ | ABAT | P80404 | 2/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OAT | P04181 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11938161 | 0.75 | GABRR1 (0.58) | SLC6A12SLC6A11SLC6A13GABRR1ABAT | |
| SCHEMBL15777485 | 0.72 | — | — | |
| SCHEMBL5722385 | 0.71 | SLC6A12 (0.39) | SLC6A12SLC6A11SLC6A13GABRR1 | |
| SCHEMBL691392 | 0.70 | GABRR1 (0.46) | SLC6A12SLC6A11SLC6A13GABRR1ABAT | |
| SCHEMBL26649407 | 0.70 | GABRR1 (0.46) | SLC6A12SLC6A11SLC6A13GABRR1ABAT | |
| SCHEMBL29830250 | 0.70 | GABRR1 (0.46) | SLC6A12SLC6A11SLC6A13GABRR1ABAT | |
| Hydrochloric Acid SCHEMBL23699865 | 0.68 | GABRR1 (0.44) | SLC6A12SLC6A11SLC6A13GABRR1ABAT | |
| Hydrochloric Acid SCHEMBL25403412 | 0.68 | GABRR1 (0.39) | SLC6A12SLC6A11SLC6A13GABRR1ABAT | |
| SCHEMBL761864 | 0.68 | — | — | |
| SCHEMBL4287590 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200281880-A1 | INACTIVATORS OF TOXOPLASMA GONDII ORNITHINE AMINOTRANSFERASE FOR TREATING TOXOPLASMOSIS AND MALARIA | NORTHWESTERN UNIVERSITY (US) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281880-A1 | INACTIVATORS OF TOXOPLASMA GONDII ORNITHINE AMINOTRANSFERASE FOR TREATING TOXOPLASMOSIS AND MALARIA | OAT, OTC, ABAT | SLC6A12 347/4885SLC6A11 73/4885SLC6A13 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.