Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25390952 | 1.00 | AGTR2 (0.48) | AGTR2FFAR4EPHX2PDE4DTSHR | |
| SCHEMBL25391356 | 1.00 | AGTR2 (0.48) | AGTR2FFAR4EPHX2PDE4DTSHR | |
| SCHEMBL6267268 | 0.91 | EPHX2 (0.47) | AGTR2FFAR4EPHX2 | |
| SCHEMBL26951503 | 0.88 | ALDH1A1 (0.44) | AGTR2EPHX2PDE4DTSHRALDH1A1 | |
| SCHEMBL26951529 | 0.88 | ALDH1A1 (0.44) | AGTR2EPHX2PDE4DTSHRALDH1A1 | |
| SCHEMBL17391191 | 0.85 | FFAR4 (0.57) | AGTR2FFAR4TSHRALDH1A1CYP1A2 | |
| SCHEMBL5447182 | 0.85 | FFAR4 (0.57) | AGTR2FFAR4TSHRALDH1A1CYP1A2 | |
| SCHEMBL29018749 | 0.85 | FFAR4 (0.57) | AGTR2FFAR4TSHRALDH1A1CYP1A2 | |
| SCHEMBL5924916 | 0.85 | FFAR4 (0.57) | AGTR2FFAR4TSHRALDH1A1CYP1A2 | |
| SCHEMBL29188003 | 0.85 | FFAR4 (0.57) | AGTR2FFAR4TSHRALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034671-B2 | Apoptosis signal-regulating kinase inhibitors and uses thereof | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2021-06-15 | — | — | US | disclosed |
| US-20200283404-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS AND USES THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283404-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS AND USES THEREOF | DAPK1, ATF1, BAD | AGTR2 322/4885FFAR4 3229/4885EPHX2 3525/4885 |
| US-11034671-B2 | Apoptosis signal-regulating kinase inhibitors and uses thereof | DAPK1, ATF1, BAD | AGTR2 322/4885FFAR4 3229/4885EPHX2 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.