SCHEMBL224066

SCHEMBL224066

CCC(CO)OC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27055120 1.00 PRKCA (0.33) PRKCATSHR
SCHEMBL14349630 1.00 PRKCA (0.33) PRKCATSHR
SCHEMBL6015013 0.86 PRKCA (0.37) PRKCATSHR
SCHEMBL10308723 0.83 TSHR (0.32) TSHR
SCHEMBL16645140 0.81
SCHEMBL14619558 0.80 TSHR (0.30) TSHR
SCHEMBL18027533 0.79 PRKCA (0.33) PRKCA
SCHEMBL13805618 0.77 PRKCA (0.32) PRKCA
SCHEMBL13539110 0.77
SCHEMBL14003862 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546238-B2 Method for producing hydrogenated conjugated diene copolymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-01-17 US claimed
EP-1525239-B1 METHOD FOR PRODUCING POLYMERS USING CONJUGATED DIENES AND VINYL AROMATIC COMPOUNDS, POLYMERS PRODUCED ACCORDING TO SAID METHOD AND USE THEREOF SASOL GERMANY GMBH (DE) 2007-09-12 EP claimed
CN-1303119-C Method for producing polymers using conjugated dienes and vinyl aromatic compounds, polymers produced according to said method and use thereof SASOL GERMANY GMBH (DE) 2007-03-07 CN claimed
US-7151147-B2 Method for producing polymers using conjugated dienes and vinyl aromatic compounds, polymers produced according to said method and use thereof SASOL GERMANY GMBH (DE) 2006-12-19 US claimed
US-20060122343-A1 Method for producing polymers using conjugated dienes and vinyl aromatic compounds, polymers produced according to said method and use thereof SASOL GERMANY GMBH (DE) 2006-06-08 US claimed
EP-0024532-B2 TERT. BUTOXYBUTANALES AND BUTANOLES AND BIS-TERT. BUTOXY-PENTANALES AND PENTANOLES, THEIR PRODUCTION AND THEIR USE AS PERFUMES BASF Aktiengesellschaft (DE) 1984-08-15 EP claimed
US-4409402-A FRAGRANCES; CHEMICAL INTERMEDIATES BASF AKTIENGESELLSCHAFT (DE) 1983-10-11 US claimed
EP-0024532-B1 TERT. BUTOXYBUTANALES AND BUTANOLES AND BIS-TERT. BUTOXY-PENTANALES AND PENTANOLES, THEIR PRODUCTION AND THEIR USE AS PERFUMES BASF Aktiengesellschaft (DE) 1982-06-23 EP claimed
EP-0024532-A1 Tert. butoxybutanales and butanoles and bis-tert. butoxy-pentanales and pentanoles, their production and their use as perfumes BASF Aktiengesellschaft (DE) 1981-03-11 EP claimed
CN-114716426-A Antiviral compounds 詹森生物制药有限公司 2022-07-08 CN disclosed
CN-105636936-B Antiviral compounds 詹森生物制药有限公司 2022-04-05 CN disclosed
US-20180111932-A1 NOVEL NAPHTHYRIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ARRHYTHMIA NOVARTIS AG (CH) 2018-04-26 US disclosed
US-20180071262-A1 SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE ABBVIE INC. (US) 2018-03-15 US disclosed
US-9546238-B2 Method for producing hydrogenated conjugated diene copolymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-01-17 US disclosed
US-4418216-A Bis-tert.-butoxypentanals and bis-tert.-butoxypentanols BASF AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
US-4415494-A BLUE-TO-BLACK COLORFAST DISPERSE, NITRO DYES; DIAZOTIZING A P-NITROANILINE AND COUPLING WITH AN N-SUBSTITUTED 1-NAPHTHYLAMINE CASSELLA AKTIENGESELLSCHAFT (DE) 1983-11-15 US disclosed
US-4409402-A FRAGRANCES; CHEMICAL INTERMEDIATES BASF AKTIENGESELLSCHAFT (DE) 1983-10-11 US disclosed
EP-0024532-B1 TERT. BUTOXYBUTANALES AND BUTANOLES AND BIS-TERT. BUTOXY-PENTANALES AND PENTANOLES, THEIR PRODUCTION AND THEIR USE AS PERFUMES BASF Aktiengesellschaft (DE) 1982-06-23 EP disclosed
EP-0036545-A1 Water insoluble monoazo dyes, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1981-09-30 EP disclosed
EP-0024532-A1 Tert. butoxybutanales and butanoles and bis-tert. butoxy-pentanales and pentanoles, their production and their use as perfumes BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180111932-A1 NOVEL NAPHTHYRIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ARRHYTHMIA SCN1B, SCN3A, SCN5A PRKCA 1883/4885TSHR 1271/4885
US-20180071262-A1 SPIROCYCLIC HAT INHIBITORS AND METHODS FOR THEIR USE KAT2B, HDAC1, HDAC9 PRKCA 3314/4885TSHR 396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.