Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874151 | 0.96 | LMNA (0.39) | LMNATSHRTHPOFFAR3LCK | |
| SCHEMBL14932100 | 0.78 | CA4 (0.32) | LMNATSHRALDH1A1CA4 | |
| SCHEMBL7521130 | 0.76 | — | — | |
| SCHEMBL124447 | 0.73 | — | — | |
| SCHEMBL354063 | 0.73 | LMNA (0.42) | LMNATSHRTHPOFFAR3LCK | |
| SCHEMBL3894976 | 0.73 | — | — | |
| SCHEMBL1925712 | 0.73 | — | — | |
| SCHEMBL24445848 | 0.70 | — | — | |
| SCHEMBL16599779 | 0.70 | — | — | |
| SCHEMBL9818516 | 0.70 | TSHR (0.44) | LMNATSHRTHPOFFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150258220-A1 | MAGNETIC RESONANCE IMAGING AND/OR SPECTROSCOPY CONTRAST AGENTS AND METHODS OF USE THEREOF | UNIV DUKE (US) | 2015-09-17 | — | — | US | disclosed |
| US-8980225-B2 | Magnetic resonance imaging and/or spectroscopy contrast agents and methods of use thereof | DUKE UNIVERSITY (US) | 2015-03-17 | — | — | US | disclosed |
| US-20110195028-A1 | MAGNETIC RESONANCE IMAGING AND/OR SPECTROSCOPY CONTRAST AGENTS AND METHODS OF USE THEREOF | DUKE UNIVERSITY | 2011-08-11 | — | — | US | disclosed |
| WO-2010014893-A2 | MAGNETIC RESONANCE IMAGING AND/OR SPECTROSCOPY CONTRAST AGENTS AND METHODS OF USE THEREOF | DUKE UNIVERSITY (US) | 2010-02-04 | — | — | WO | disclosed |