SCHEMBL28874151

SCHEMBL28874151

CC(=O)C(O)(C(C)=O)C(C)=O.[AlH3]

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
TSHR P16473 2/20 0.36
THPO P40225 1/20 0.36
FFAR3 O14843 1/20 0.36
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
ALDH1A1 P00352 1/20 0.35
CA1 P00915 2/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2240709 0.96 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL14932100 0.74 CA4 (0.32) LMNATSHRALDH1A1
SCHEMBL7521130 0.73
SCHEMBL354063 0.70 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL124447 0.70
SCHEMBL1925712 0.70
SCHEMBL27369862 0.70 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL3894976 0.70
SCHEMBL3966743 0.70 LMNA (0.42) LMNATSHRTHPOFFAR3LCK
SCHEMBL4455750 0.69 LMNA (0.33) LMNATSHRTHPOFFAR3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109963917-A The dispersion of beta-keto carbonyl group function organo-silicon compound 瓦克化学股份公司 2019-07-02 CN disclosed