SCHEMBL2240724

SCHEMBL2240724

O=C(OCc1ccccc1)ON1C(=O)C2C3C=CC(C3)C2C1=O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
TSHR P16473 4/20 0.52
GAA P10253 1/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
HSD11B1 P28845 1/20 0.49
LMNA P02545 1/20 0.49
HPGD P15428 1/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HSP90AA1 P07900 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11961432 0.85 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2TSHRGAAMEN1
SCHEMBL9611933 0.83 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL9247606 0.83 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL16090421 0.83 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL11043305 0.81 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TSHRGAAMEN1
SCHEMBL11419655 0.81 GAA (0.51) ALDH1A1SMN1; SMN2TSHRGAAMEN1
SCHEMBL28371429 0.80 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2TSHRGAAMEN1
SCHEMBL11038920 0.80 LMNA (0.46) ALDH1A1SMN1; SMN2TSHRGAAMEN1
SCHEMBL21987044 0.80 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL20919927 0.80 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6759170-B2 Organic carbonate additives for nonaqueous electrolyte rechargeable electrochemical cells WILSON GREATBATCH TECHNOLOGIES, INC. 2004-07-06 US claimed
US-6605385-B2 Carbonate compound has bonds of specified dissociation energy, such as dibenzyl carbonate, mixed with either the anode or the cathode active material prior to contact with its current collectors; use in defibrillators WILSON GREATBATCH LTD. 2003-08-12 US claimed
US-20030129500-A1 Organic carbonate additives for nonaqueous electrolyte rechargeable electrochemical cells GREATBATCH, INC. 2003-07-10 US claimed
US-20020136951-A1 Electrochemical cell having an electrode with a carbonate additive in the electrode active mixture GREATBATCH, INC. 2002-09-26 US claimed
EP-1244160-A1 Electrochemical cell having an electrode with a carbonate additive in the electrode active mixture Wilson Greatbatch Limited (US) 2002-09-25 EP claimed
EP-1215746-A1 Organic carbonate additives for nonaqueous electrolyte rechargeable electrochemical cells WILSON GREATBATCH LTD. (US) 2002-06-19 EP claimed
EP-0803924-B1 Organic carbonate additives for nonaqueous electrolyte in alkali metal electrochemical cells GREATBATCH W LTD (US) 2001-10-31 EP claimed
US-20010004507-A1 Organic carbonate additives for nonaqueous electrolyte rechargeable electrochemical cells GREATBATCH LTD. 2001-06-21 US claimed
US-6221534-B1 CATHODE IS INORGANIC REACTION PRODUCT CONTAINING VANADIUM OXIDE AND SILVER OXIDE WILSON GREATBATCH LTD. 2001-04-24 US claimed
EP-1005098-A2 Alkali metal electrochemical cell having an improved cathode activated with a nonaqueous electrolyte having a passivation inhibitor additive WILSON GREATBATCH LTD. (US) 2000-05-31 EP claimed
EP-0996187-A1 Organic carbonate additives for nonaqueous electrolyte rechargeable cells WILSON GREATBATCH LTD. (US) 2000-04-26 EP claimed
US-5753389-A Organic carbonate additives for nonaqueous electrolyte in alkali metal electrochemical cells WILSON GREATBATCH LTD. (US) 1998-05-19 US claimed
EP-0803924-A2 Organic carbonate additives for nonaqueous electrolyte in alkali metal electrochemical cells WILSON GREATBATCH LTD. (US) 1997-10-29 EP claimed
JP-61036261-A None JP disclosed
EP-3891162-B1 NOVEL DERIVATIVES OF N-3\"-GUANIDINO-2,5-DIDEOXY-5-FLUORO-4,6-DISUBSTITUTED-STREPTAMINE AMINOGLYCOSIDE ANTIBIOTICS AGILEBIOTICS B V (NL) 2024-03-06 EP disclosed
US-20220127297-A1 Novel Antibacterial 3\"-Derivatives Of 4,6-Disubstituted 2,5-Dideoxystreptamine Aminoglycoside Antibiotics AGILEBIOTICS B.V. (NL) 2022-04-28 US disclosed
EP-0083923-A2 Aminoacyl-containing dipeptide derivatives useful as antihypertensives MERCK & CO. INC. (US) 1983-07-20 EP disclosed
US-4219644-A Fortimicins AH and AI ABBOTT LABORATORIES (US) 1980-08-26 US disclosed
US-4213972-A BACTERICIDES ABBOTT LABORATORIES (US) 1980-07-22 US disclosed
US-4181797-A 1-N-(ω-amino-α-hydroxyalkanoyl) derivatives of 4'-deoxy-6'-N-methylkanamycin A BRISTOL-MYERS COMPANY (US) 1980-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127297-A1 Novel Antibacterial 3\"-Derivatives Of 4,6-Disubstituted 2,5-Dideoxystreptamine Aminoglycoside Antibiotics ABCC1, AMPD3, MRPS35 ALDH1A1 2961/4885SMN1; SMN2 4353/4885TSHR 4302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.