SCHEMBL2240755

SCHEMBL2240755

OCCCC[SiH]1CCCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11030067 0.94
SCHEMBL15757857 0.89
SCHEMBL356969 0.87
SCHEMBL27975077 0.85
SCHEMBL183518 0.81
SCHEMBL3823579 0.81 NFKB1 (0.30)
SCHEMBL15535194 0.79
SCHEMBL8944328 0.79
SCHEMBL3823714 0.79
SCHEMBL461328 0.79 DNM1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4971786-A CATIONIC AMMONIUM SURFACTANTS, QUATERNIZED HYDROXYALKYL CELLULOSE AND A SILOXANE COPOLYMER L'OREAL (FR) 1990-11-20 US claimed
JP-2138205-A None JP disclosed
EP-2559534-B1 Composition and method for casting manufacturing RAYTHEON TECH CORP (US) 2023-10-25 EP disclosed
EP-2539091-B1 CASTING CORE FOR TURBINE ENGINE COMPONENTS AND METHOD OF MAKING THE SAME SIEMENS ENERGY INC (US) 2020-10-21 EP disclosed
EP-2559533-B1 Casting UNITED TECHNOLOGIES CORP (US) 2020-04-15 EP disclosed
EP-3036055-B1 TURBINE COMPONENT CASTING CORE WITH HIGH RESOLUTION REGION SIEMENS ENERGY INC (US) 2019-07-03 EP disclosed
US-10207315-B2 Systems, devices, and/or methods for manufacturing castings UNITED TECHNOLOGIES CORPORATION (US) 2019-02-19 US disclosed
EP-3036055-A1 TURBINE COMPONENT CASTING CORE WITH HIGH RESOLUTION REGION Siemens Energy, Inc. (US) 2016-06-29 EP disclosed
US-9315663-B2 Systems, devices, and/or methods for manufacturing castings MIKRO SYSTEMS, INC. (US) 2016-04-19 US disclosed
US-20160082502-A1 Systems, Devices, and/or Methods for Manufacturing Castings RTX CORPORATION 2016-03-24 US disclosed
US-20110189440-A1 Systems, Devices, and/or Methods for Manufacturing Castings MIKRO SYSTEMS, INC. (US) 2011-08-04 US disclosed
WO-2010036801-A2 SYSTEMS, DEVICES, AND/OR METHODS FOR MANUFACTURING CASTINGS APPLEBY MICHAEL (US) 2010-04-01 WO disclosed
US-6537533-B2 For for conditioning hair UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-03-25 US disclosed
US-20020143063-A1 Hair conditioner composition that is non-irritating to the eyes UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-10-03 US disclosed
US-4971786-A CATIONIC AMMONIUM SURFACTANTS, QUATERNIZED HYDROXYALKYL CELLULOSE AND A SILOXANE COPOLYMER L'OREAL (FR) 1990-11-20 US disclosed
JP-H02138205-A COMPOSITION FOR TREATING HAIR L'OREAL SA 1990-05-28 JP disclosed
US-4785041-A PASSIVATION COATINGS OF CURABLE POLYSILOXANES DOW CORNING CORPORATION (US) 1988-11-15 US disclosed
US-4543398-A Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-09-24 US disclosed
EP-0127321-A1 Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-12-05 EP disclosed
US-3957715-A SILICONE RESIN HOWMET CORPORATION (US) 1976-05-18 US disclosed