SCHEMBL22407559

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22407333	0.84	ENPP1 (0.74)	ENPP1ENPP3CA12CA1CA2
	SCHEMBL20770893	0.83	ENPP1 (1.00)	ENPP1ENPP3CA12CA1CA2
	SCHEMBL30105952	0.83	ENPP1 (1.00)	ENPP1ENPP3CA12CA1CA2
	SCHEMBL22407557	0.82	ENPP3 (0.48)	ENPP1ENPP3HDAC1PIK3CAGRM2
	SCHEMBL25683027	0.81	ENPP1 (0.69)	ENPP1ENPP3CA12CA1CA2
	SCHEMBL20782623	0.81	ENPP1 (0.69)	ENPP1ENPP3PIK3CAKIF11PIK3CD
	SCHEMBL24010160	0.80	ENPP3 (0.46)	ENPP1ENPP3PIK3CAGRM2PIK3CD
	SCHEMBL20782680	0.79	ENPP1 (0.64)	ENPP1ENPP3HDAC1CA12CA1
	SCHEMBL22407352	0.79	ENPP1 (0.86)	ENPP1ENPP3CA12CA1CA2
	SCHEMBL22407575	0.78	ENPP1 (0.72)	ENPP1ENPP3HDAC1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.