Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.42 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862726 | 1.00 | CYP1A2 (0.49) | CYP1A2MALT1BIRC3NPC1RAB9A | |
| SCHEMBL17293093 | 0.87 | CYP1A2 (0.51) | CYP1A2MALT1BIRC3NPC1RAB9A | |
| SCHEMBL17293094 | 0.87 | CYP1A2 (0.51) | CYP1A2MALT1BIRC3NPC1RAB9A | |
| SCHEMBL18787657 | 0.86 | MALT1 (0.52) | MALT1BIRC3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17293052 | 0.86 | MALT1 (0.52) | MALT1BIRC3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17293051 | 0.86 | MALT1 (0.52) | MALT1BIRC3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18839707 | 0.86 | MALT1 (0.41) | CYP1A2MALT1BIRC3NPC1RAB9A | |
| SCHEMBL18839705 | 0.86 | MALT1 (0.41) | CYP1A2MALT1BIRC3NPC1RAB9A | |
| SCHEMBL20455857 | 0.84 | CYP1A2 (0.56) | CYP1A2MALT1BIRC3NPC1RAB9A | |
| SCHEMBL20921920 | 0.80 | CYP1A2 (0.38) | CYP1A2MALT1BIRC3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200289514-A1 | Novel Pyrazolo Pyrimidine Derivatives | NOVARTIS PHARMA AG (CH) | 2020-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200289514-A1 | Novel Pyrazolo Pyrimidine Derivatives | MMEL1, PPME1, CTSC | CYP1A2 2769/4885MALT1 4/4885BIRC3 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.