SCHEMBL224091

SCHEMBL224091

Cc1ccc(Cc2ccc(C)c(C(C)(C)C)c2O)c(O)c1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.41
CYP2C9 P11712 4/20 0.40
CYP2C19 P33261 4/20 0.40
HIF1A Q16665 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
CYP2D6 P10635 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GABRA1 P14867 2/20 0.36
GABRB2 P47870 2/20 0.36
AMY1A P0DUB6 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
CYP1A2 P05177 1/20 0.32
CA2 P00918 2/20 0.32
ALDH1A1 P00352 2/20 0.31
POLB P06746 1/20 0.31
TYR P14679 1/20 0.31
TP53 P04637 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5173019 0.85 AMY1A (0.58) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL30646674 0.84 TYR (0.43) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1860671 0.83 CYP2C9 (0.43) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL394653 0.80 GABRA1 (0.48) CYP2C9CYP2C19HIF1ASMN1; SMN2CYP2D6
SCHEMBL31597226 0.80 GABRA1 (0.48) CYP2C9CYP2C19HIF1ASMN1; SMN2CYP2D6
SCHEMBL28358742 0.80 TYR (0.47) CYP2C9CYP2D6TYRTP53PTGS2
SCHEMBL15955216 0.79 HSPA5 (0.46) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL1053673 0.76 ESR1 (0.41) CYP2C9CYP2C19SMN1; SMN2HSD17B10GABRA1
SCHEMBL285281 0.74 GABRA1 (0.54) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29636322 0.74 GABRA1 (0.54) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428216-B2 Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures ACUSHNET COMPANY (US) 2019-10-01 US disclosed
US-20190192922-A1 GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE ACUSHNET COMPANY (US) 2019-06-27 US disclosed
US-10252115-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2019-04-09 US disclosed
US-10220263-B2 Golf balls comprising medium hardness gradient core ACUSHNET COMPANY (US) 2019-03-05 US disclosed
US-10130848-B2 Golf ball multilayer core having a gradient quotient ACUSHNET COMPANY (US) 2018-11-20 US disclosed
US-20180318654-A1 GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER ACUSHNET COMPANY (US) 2018-11-08 US disclosed
US-10112081-B2 Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer ACUSHNET COMPANY (US) 2018-10-30 US disclosed
US-10035046-B2 Multilayer core golf ball having hardness gradient within and between each core layer ACUSHNET COMPANY (US) 2018-07-31 US disclosed
US-10029151-B2 Multi-layer cover golf ball having a high acid casing layer ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-10029150-B2 Golf ball having medium positive gradient quotient and low trans content ACUSHNET COMPANY (US) 2018-07-24 US disclosed
US-20090011863-A1 Negative Hardness Gradient Inner Core for Dual Core Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-20090008832-A1 Negative Hardness Gradient Core Produced from a Low, Temperature-Based Cure Cycle Index ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011855-A1 Golf Ball Core with Soft Outer Transition Volume and Negative Hardness Gradient ACUSHNET COMPANY 2009-01-08 US disclosed
US-20090011867-A1 Multi-Layer Core Golf Ball Having Opposing Hardness Gradient with Steep Gradient Outer Core Layer JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-01-08 US disclosed
US-7429221-B1 Negative hardness gradient outer core layer for dual core golf ball ACUSHNET COMPANY (US) 2008-09-30 US disclosed
US-7410429-B1 Negative hardness gradient inner core for dual core golf ball ACUSHNET COMPANY (US) 2008-08-12 US disclosed
US-20080153629-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-26 US disclosed
US-20080146380-A1 Thick Outer Cover Layer Golf Ball ACUSHNET COMPANY 2008-06-19 US disclosed
US-20080146378-A1 Thick Inner Cover Multi-layer Golf Ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2008-06-19 US disclosed
US-6208410-B1 Image forming apparatus FUJI PHOTO FILM CO., LTD. (JP) 2001-03-27 US disclosed