Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | PKM | P14618 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359764 | 0.87 | RAB9A (0.49) | RAB9ANPC1ALDH1A1PKMNPSR1 | |
| SCHEMBL2682040 | 0.83 | RAB9A (0.71) | RAB9ANPC1ALDH1A1PKMNPSR1 | |
| SCHEMBL11327867 | 0.83 | RAB9A (0.66) | RAB9ANPC1ALDH1A1PKMNPSR1 | |
| SCHEMBL8916188 | 0.81 | RAB9A (0.63) | RAB9ANPC1ALDH1A1PKMNPSR1 | |
| SCHEMBL1467809 | 0.79 | RAB9A (0.61) | RAB9ANPC1ALDH1A1PKMNPSR1 | |
| SCHEMBL9028468 | 0.79 | RAB9A (0.70) | RAB9ANPC1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL4021933 | 0.79 | NPC1 (0.59) | RAB9ANPC1ALDH1A1PKMNPSR1 | |
| SCHEMBL525427 | 0.79 | RAB9A (0.61) | RAB9ANPC1ALDH1A1PKMNPSR1 | |
| SCHEMBL5805584 | 0.79 | RAB9A (0.61) | RAB9ANPC1ALDH1A1PKMNPSR1 | |
| SCHEMBL29399796 | 0.79 | RAB9A (0.61) | RAB9ANPC1ALDH1A1PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389395-B1 | RAFT POLYMERISATION | COMMW SCIENT IND RES ORG (AU) | 2017-03-29 | — | — | EP | disclosed |
| US-9340498-B2 | Raft polymerisation | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESERACH ORGANISATION (AU) | 2016-05-17 | — | — | US | disclosed |
| US-20120004381-A1 | RAFT POLYMERISATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-01-05 | — | — | US | disclosed |
| EP-2389395-A1 | RAFT POLYMERISATION | Commonwealth Scientific and Industrial Research Organisation (AU) | 2011-11-30 | — | — | EP | disclosed |
| US-20110256644-A1 | MASKS FOR MICROLITHOGRAPHY AND METHODS OF MAKING AND USING SUCH MASKS | MICRON TECHNOLOGY, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2010083569-A1 | RAFT POLYMERISATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-07-29 | — | — | WO | disclosed |
| US-5696140-A | FOR TREATMENT OF ASTHMA, ALLERGIES, NERVOUS SYSTEM DISORDERS OR CANCER | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1997-12-09 | — | — | US | disclosed |
| US-5563160-A | NERVOUS SYSTEM DISORDERS, ANTIHISTAMINE, ANTIALLERGENS | Leo Pharmaceutical Products Ltd. A/S (L.o slashed.vens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1996-10-08 | — | — | US | disclosed |
| EP-0660823-B1 | N-CYANO-N'-PYRIDYLGUANIDINES AS SEROTONIN ANTAGONISTS | LEO PHARM PROD LTD (DK) | 1996-08-14 | — | — | EP | disclosed |
| EP-0660823-A1 | N-CYANO-N'-PYRIDYLGUANIDINES AS SEROTONIN ANTAGONISTS. | LEO PHARM PROD LTD (DK) | 1995-07-05 | — | — | EP | disclosed |
| US-4975443-A | Fungicidal pyridyl iminocarbonates | ICI AMERICAS INC. (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0314430-A2 | Fungicidal pyridyl iminocarbonates | ICI AMERICAS INC. (US) | 1989-05-03 | — | — | EP | disclosed |
| US-4824854-A | PREVENTIVE, CURATIVE | ICI AMERICAS INC. (US) | 1989-04-25 | — | — | US | disclosed |
| US-RE31244-E | Antihypertensive pyridylguanidine compounds | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1983-05-17 | — | — | US | disclosed |
| US-4271167-A | ANTHELMINTICS | RHONE-POULENC INDUSTRIES (FR) | 1981-06-02 | — | — | US | disclosed |
| US-4167571-A | Thiazoline derivatives | RHONE-POULENC INDUSTRIES (FR) | 1979-09-11 | — | — | US | disclosed |
| US-4039550-A | ANTHELMINTIC AGENTS | STERLING DRUG INC. (US) | 1977-08-02 | — | — | US | disclosed |
| US-4009279-A | 2-IMINO-1,3-DITHIETANES | AMERICAN CYANAMID COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3997668-A | INSECTICIDES, MITICIDE | AMERICAN CYANAMID COMPANY (US) | 1976-12-14 | — | — | US | disclosed |
| US-3975528-A | Insecticidal 2-imino-1,3-dithietane derivatives | AMERICAN CYANAMID COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004381-A1 | RAFT POLYMERISATION | OXGR1, FRG1, MSR1 | RAB9A 3808/4885NPC1 340/4885ALDH1A1 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.