Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22412620 | 0.84 | L3MBTL1 (0.56) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL22412576 | 0.82 | MAPT (0.59) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7704030 | 0.82 | ATM (0.54) | MEN1KMT2APOLBATMMAPT | |
| SCHEMBL22412644 | 0.78 | MEN1 (0.53) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL22407708 | 0.76 | KDM4E (0.70) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL22407651 | 0.76 | KDM4E (0.61) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL22412508 | 0.76 | POLB (0.50) | MEN1KMT2APOLBMAPTL3MBTL1 | |
| SCHEMBL12259083 | 0.75 | ALDH1A1 (0.56) | POLBALDH1A1SMN1; SMN2TDP1HTT | |
| SCHEMBL12258816 | 0.75 | ALDH1A1 (0.56) | POLBALDH1A1SMN1; SMN2TDP1HTT | |
| SCHEMBL1911484 | 0.75 | ALDH1A1 (0.56) | POLBALDH1A1SMN1; SMN2TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3938345-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | Nocion Therapeutics, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020185830-A1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | Nocion Therapeutics, Inc. (US) | 2020-09-17 | — | — | WO | disclosed |