Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17820115 | 0.82 | RAB9A (0.39) | POLBRAB9AKMT2AMAPTNPC1 | |
| SCHEMBL17819791 | 0.82 | NPC1 (0.37) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL22426061 | 0.77 | CA12 (0.48) | RAB9AMAPTNPC1CYP1A2CYP2C19 | |
| SCHEMBL29177320 | 0.73 | NPC1 (0.49) | POLBRAB9AKMT2AMAPTNPC1 | |
| SCHEMBL11597646 | 0.73 | MAOA (0.41) | RAB9AKMT2AMAPTCYP1A2ADRA2A | |
| SCHEMBL4647917 | 0.73 | NPC1 (0.77) | POLBRAB9AKMT2AMAPTNPC1 | |
| SCHEMBL12610862 | 0.73 | CYP1A2 (0.72) | POLBRAB9AKMT2AMAPTNPC1 | |
| SCHEMBL27091154 | 0.73 | POLB (0.46) | POLBRAB9AKMT2AMAPTNPC1 | |
| SCHEMBL30494024 | 0.70 | NPC1 (0.65) | POLBRAB9AKMT2AMAPTNPC1 | |
| SCHEMBL11896022 | 0.70 | NPC1 (0.70) | POLBRAB9AKMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210404958-A1 | STIMULATED RAMAN COUPLED FLUORESCENCE SPECTROSCOPY AND MICROSCOPY SYSTEM AND METHOD | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-12-30 | — | — | US | disclosed |
| WO-2020186026-A1 | STIMULATED RAMAN COUPLED FLUORESCENCE SPECTROSCOPY AND MICROSCOPY SYSTEM AND METHOD | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-09-17 | — | — | WO | disclosed |