Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713949 | 0.93 | LMNA (0.57) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL6276301 | 0.90 | LMNA (0.41) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL13538450 | 0.89 | LMNA (0.59) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL10930838 | 0.87 | LMNA (0.68) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL2196184 | 0.85 | LMNA (0.71) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| Butane SCHEMBL3681072 | 0.85 | LMNA (0.66) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL1109721 | 0.85 | LMNA (0.71) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL2516960 | 0.85 | LMNA (0.71) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL925671 | 0.85 | LMNA (0.71) | LMNATSHRMAPTMAPK1ALDH1A1 | |
| SCHEMBL28810094 | 0.85 | LMNA (0.66) | LMNATSHRMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3938045-A1 | SALTS OF A ISOCHROMANYL COMPOUND AND CRYSTALLINE FORMS, PROCESSES FOR PREPARING, THERAPEUTIC USES, AND PHARMACEUTICAL COMPOSITIONS THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| WO-2020186165-A1 | SALTS OF A ISOCHROMANYL COMPOUND AND CRYSTALLINE FORMS, PROCESSES FOR PREPARING, THERAPEUTIC USES, AND PHARMACEUTICAL COMPOSITIONS THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2020-09-17 | — | — | WO | disclosed |