Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22415171 | 0.81 | MEN1 (0.43) | DGAT1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14445416 | 0.79 | DGAT1 (0.51) | DGAT1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL22415211 | 0.74 | DGAT1 (0.46) | DGAT1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13342190 | 0.73 | NAPRT (0.52) | DGAT1MAPTL3MBTL1NAPRTRAB9A | |
| SCHEMBL17778492 | 0.73 | NAPRT (0.52) | DGAT1MAPTL3MBTL1NAPRTRAB9A | |
| SCHEMBL23845464 | 0.73 | NAPRT (0.52) | DGAT1LMNAMAPTL3MBTL1NAPRT | |
| SCHEMBL1726660 | 0.73 | NAPRT (0.52) | DGAT1MAPTL3MBTL1NAPRTRAB9A | |
| SCHEMBL30515503 | 0.73 | NAPRT (0.52) | DGAT1MAPTL3MBTL1NAPRTRAB9A | |
| SCHEMBL1726659 | 0.73 | NAPRT (0.52) | DGAT1MAPTL3MBTL1NAPRTRAB9A | |
| SCHEMBL14433314 | 0.71 | DGAT1 (0.46) | DGAT1MEN1KMT2AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257851-B1 | SALT FORM AND CRYSTAL FORM OF 1,2,5 THIADIAZOLIDIN-1,1-DIOXIDE, PREPARATION METHOD THEREOF AND INTERMEDIATE | JIANGSU KANION PHARMACEUTICAL CO LTD (CN) | 2020-09-09 | — | — | EP | disclosed |