Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30515503 | 0.84 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL1726659 | 0.84 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL13342190 | 0.84 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL1726660 | 0.84 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL17778492 | 0.84 | NAPRT (0.52) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL14445416 | 0.79 | DGAT1 (0.51) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL19719710 | 0.79 | NAPRT (0.47) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL9769007 | 0.78 | NAPRT (0.50) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL14433314 | 0.78 | DGAT1 (0.46) | NAPRTADRA2AADRA2BADRA2CDGAT1 | |
| SCHEMBL388168 | 0.75 | NAPRT (0.67) | NAPRTADRA2AADRA2BADRA2CDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188938-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | AKEBIA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |