Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | MMP8 | P22894 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696413 | 0.86 | HSD17B10 (0.77) | HSD17B10TSHRKMT2AGAAMEN1 | |
| SCHEMBL29005257 | 0.85 | FKBP1A (0.58) | HSD17B10MMP8TSHRFKBP1AKMT2A | |
| SCHEMBL27630775 | 0.84 | HSD17B10 (0.75) | HSD17B10TSHRKMT2AGAAALDH1A1 | |
| SCHEMBL26802538 | 0.84 | HSD17B10 (0.75) | HSD17B10TSHRKMT2AGAAALDH1A1 | |
| SCHEMBL22479134 | 0.83 | HSD17B10 (1.00) | HSD17B10CHRM1 | |
| SCHEMBL2162843 | 0.83 | MMP8 (0.64) | HSD17B10MMP8TSHRFKBP1AKMT2A | |
| SCHEMBL5479757 | 0.83 | MMP8 (0.64) | HSD17B10MMP8TSHRFKBP1AKMT2A | |
| SCHEMBL2162836 | 0.83 | MMP8 (0.64) | HSD17B10MMP8TSHRFKBP1AKMT2A | |
| SCHEMBL18435192 | 0.82 | MMP8 (0.60) | HSD17B10MMP8TSHRFKBP1AKMT2A | |
| SCHEMBL16252288 | 0.82 | MMP8 (0.60) | HSD17B10MMP8TSHRFKBP1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3705476-A1 | 2-(1H-PYRAZOL-3-YL) PHENOL COMPOUND AND USE THEREOF | Beijing Jialin Pharmaceutical Inc. (CN) | 2020-09-09 | — | — | EP | disclosed |