Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 8/20 | 0.54 |
| ▸ | HCK | P08631 | 8/20 | 0.48 |
| ▸ | FLT3 | P36888 | 7/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | KIF5B | P33176 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ABL2 | P42684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22418432 | 0.84 | BTK (0.44) | RIPK2HCKRETKCNH2SRC | |
| SCHEMBL28898414 | 0.84 | RIPK2 (0.52) | RIPK2HCKFLT3KDRSRC | |
| SCHEMBL22418417 | 0.81 | NEK7 (0.51) | RIPK2HCKFLT3RETKIF5B | |
| SCHEMBL30441772 | 0.75 | RET (0.47) | RIPK2FLT3RETKIF5BKDR | |
| SCHEMBL20351599 | 0.74 | SRC (0.61) | RIPK2KDRSRCABL1EGFR | |
| SCHEMBL2071828 | 0.74 | FLT3 (0.46) | RIPK2FLT3RETKIF5BKDR | |
| SCHEMBL16752356 | 0.74 | SRC (0.63) | HCKFLT3RETKDRSRC | |
| SCHEMBL30056817 | 0.74 | SRC (0.63) | HCKFLT3RETKDRSRC | |
| SCHEMBL16752372 | 0.73 | LCK (0.59) | HCKFLT3RETKDRSRC | |
| SCHEMBL22418414 | 0.73 | BTK (0.55) | RIPK2HCKRETKCNH2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182188-A1 | SUBSTITUTED HETEROARYL COMPOUND, COMPOSITION OF SAME, AND USES THEREOF | 习峰 | 2020-09-17 | — | — | WO | disclosed |