Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.47 |
| ▸ | KIF5B | P33176 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 11/20 | 0.46 |
| ▸ | NEK7 | Q8TDX7 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ABL2 | P42684 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569254 | 0.82 | LCK (0.42) | SRCFLT3 | |
| SCHEMBL28898414 | 0.81 | RIPK2 (0.52) | KDRRIPK2SRCABL1EGFR | |
| SCHEMBL29175934 | 0.76 | RIPK2 (0.64) | RETKIF5BKDRKCNH2CCDC6 | |
| SCHEMBL30442066 | 0.75 | FLT3 (0.51) | RETFLT3 | |
| SCHEMBL22418418 | 0.75 | RIPK2 (0.54) | RETKIF5BKDRKCNH2CCDC6 | |
| SCHEMBL22418417 | 0.73 | NEK7 (0.51) | RETKIF5BKDRKCNH2CCDC6 | |
| SCHEMBL20351599 | 0.72 | SRC (0.61) | KDRRIPK2SRCABL1EGFR | |
| SCHEMBL2074527 | 0.71 | ABL1 (0.50) | RETKIF5BKDRKCNH2CCDC6 | |
| SCHEMBL2074179 | 0.71 | SRC (0.59) | RETKIF5BKDRKCNH2CCDC6 | |
| SCHEMBL28928812 | 0.71 | SRC (0.66) | RIPK2SRCABL1EGFRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689991-B | Substituted heteroaryl compounds, compositions and uses thereof | 习峰 | 2023-06-09 | — | — | CN | disclosed |