Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 7/20 | 0.52 |
| ▸ | SRC | P12931 | 6/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | ABL1 | P00519 | 3/20 | 0.51 |
| ▸ | ABL2 | P42684 | 3/20 | 0.51 |
| ▸ | HCK | P08631 | 7/20 | 0.51 |
| ▸ | FLT3 | P36888 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | LYN | P07948 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22418418 | 0.84 | RIPK2 (0.54) | RIPK2SRCEGFRABL1ABL2 | |
| SCHEMBL30441772 | 0.81 | RET (0.47) | RIPK2SRCEGFRABL1ABL2 | |
| SCHEMBL20351599 | 0.81 | SRC (0.61) | RIPK2SRCEGFRABL1ABL2 | |
| SCHEMBL28677115 | 0.79 | SRC (0.54) | SRCFLT3LCKKDRTEK | |
| SCHEMBL28669572 | 0.79 | EGFR (0.56) | RIPK2SRCEGFRABL1ABL2 | |
| SCHEMBL28669568 | 0.79 | EGFR (0.56) | RIPK2SRCEGFRABL1ABL2 | |
| SCHEMBL16752372 | 0.78 | LCK (0.59) | SRCEGFRABL1HCKFLT3 | |
| SCHEMBL2075445 | 0.77 | SRC (0.63) | RIPK2SRCEGFRABL1ABL2 | |
| SCHEMBL2072372 | 0.76 | SRC (0.60) | RIPK2SRCEGFRABL1ABL2 | |
| SCHEMBL28675253 | 0.76 | LCK (0.39) | RIPK2SRCFLT3LCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111689991-B | Substituted heteroaryl compounds, compositions and uses thereof | 习峰 | 2023-06-09 | — | — | CN | disclosed |
| CN-111689991-A | Substituted heteroaryl compounds, compositions and uses thereof | 习峰 | 2020-09-22 | — | — | CN | disclosed |