Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22418641 | 0.80 | ATM (0.42) | — | |
| SCHEMBL25766872 | 0.80 | NPY5R (0.38) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL38659036 | 0.80 | ATM (0.42) | — | |
| SCHEMBL14984908 | 0.80 | NPY5R (0.38) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL6653691 | 0.80 | CHRM2 (0.52) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL10449210 | 0.80 | CHRM2 (0.52) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL14141163 | 0.80 | CHRM2 (0.52) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL19934329 | 0.78 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL29308581 | 0.78 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL12990820 | 0.75 | CHRM2 (0.48) | CHRM2CHRM4CHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |