Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 11/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30823776 | 1.00 | ADRA1A (0.54) | ADRA1AHPGDGRIN1GRIN2BHRH3 | |
| SCHEMBL30823783 | 0.96 | ADRA1A (0.53) | ADRA1AHPGDGRIN1GRIN2BHRH3 | |
| SCHEMBL22418715 | 0.96 | ADRA1A (0.53) | ADRA1AHPGDGRIN1GRIN2BHRH3 | |
| SCHEMBL25388074 | 0.89 | SLC18A3 (0.50) | ADRA1AHPGDPOLB | |
| SCHEMBL26258116 | 0.89 | SLC18A3 (0.50) | ADRA1AHPGDPOLB | |
| SCHEMBL28999383 | 0.89 | SLC18A3 (0.50) | ADRA1AHPGDPOLB | |
| SCHEMBL26249020 | 0.86 | ADRA1A (0.58) | ADRA1A | |
| SCHEMBL30000155 | 0.85 | PRMT5 (0.51) | ADRA1AHPGDPOLB | |
| SCHEMBL25386691 | 0.85 | PRMT5 (0.51) | ADRA1AHPGDPOLB | |
| SCHEMBL26255096 | 0.85 | PRMT5 (0.51) | ADRA1AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330009-B | Azacyclic compounds, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| EP-4209485-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | Innovstone Therapeutics Limited (CN) | 2023-07-12 | — | — | EP | disclosed |
| CN-113330009-A | Nitrogen heterocyclic compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| WO-2020182018-A1 | NITROGEN HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2020-09-17 | — | — | WO | disclosed |
| WO-2020182018-A1 | NITROGEN HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2020-09-17 | — | — | WO | disclosed |