Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25388074 | 1.00 | SLC18A3 (0.50) | SLC18A3PRMT5WDR77HPGDADRA1A | |
| SCHEMBL28999383 | 1.00 | SLC18A3 (0.50) | SLC18A3PRMT5WDR77HPGDADRA1A | |
| SCHEMBL26252134 | 0.93 | PRMT5 (0.51) | SLC18A3PRMT5WDR77HPGDADRA1A | |
| SCHEMBL26255096 | 0.93 | PRMT5 (0.51) | SLC18A3PRMT5WDR77HPGDADRA1A | |
| SCHEMBL25386691 | 0.93 | PRMT5 (0.51) | SLC18A3PRMT5WDR77HPGDADRA1A | |
| SCHEMBL30000155 | 0.93 | PRMT5 (0.51) | SLC18A3PRMT5WDR77HPGDADRA1A | |
| SCHEMBL27172349 | 0.93 | PRMT5 (0.51) | SLC18A3PRMT5WDR77HPGDADRA1A | |
| SCHEMBL22418703 | 0.89 | ADRA1A (0.54) | HPGDADRA1APOLB | |
| SCHEMBL30823776 | 0.89 | ADRA1A (0.54) | HPGDADRA1APOLB | |
| SCHEMBL22418715 | 0.85 | ADRA1A (0.53) | HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209485-A1 | COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF | Innovstone Therapeutics Limited (CN) | 2023-07-12 | — | — | EP | disclosed |