⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL224656 | 0.79 | — | — | |
| SCHEMBL407446 | 0.79 | — | — | |
| SCHEMBL2347090 | 0.75 | — | — | |
| SCHEMBL2347896 | 0.75 | — | — | |
| SCHEMBL3645962 | 0.75 | — | — | |
| SCHEMBL23531222 | 0.75 | — | — | |
| SCHEMBL78405 | 0.72 | — | — | |
| SCHEMBL17514559 | 0.72 | — | — | |
| SCHEMBL10804809 | 0.71 | PTGS2 (0.31) | — | |
| SCHEMBL436848 | 0.70 | NPC1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118291407-A | Application of short-chain dehydrogenase and mutant thereof | 沈阳药科大学 | 2024-07-05 | — | — | CN | claimed |
| CN-111073919-B | Method for preparing (S) -2- (3, 4-difluorophenyl) oxirane | 尚科生物医药（上海）有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118028259-A | Short-chain dehydrogenase and application thereof | 河北工业大学 | 2024-05-14 | — | — | CN | claimed |
| CN-115109759-B | Carbonyl reductase LsCR mutant, engineering bacterium and application thereof in preparation of chiral alcohol by asymmetric reduction of carbonyl compound | 浙江工业大学 | 2024-05-03 | — | — | CN | claimed |
| CN-111763662-B | Ketoreductase and application thereof in synthesis of ticagrelor intermediate | 上海京新生物医药有限公司 | 2023-12-19 | — | — | CN | claimed |
| WO-2023239768-A1 | TRICYCLIC TRIAZOLO COMPOUNDS AS DGK INHIBITORS | INCYTE CORPORATION (US) | 2023-12-14 | — | — | WO | claimed |
| US-20230399342-A1 | TRICYCLIC TRIAZOLO COMPOUNDS AS DGK INHIBITORS | INCYTE CORPORATION | 2023-12-14 | — | — | US | claimed |
| CN-115011573-B | Alcohol dehydrogenase mutant and application thereof | 浙江大学 | 2023-12-12 | — | — | CN | claimed |
| EP-3901147-B1 | ACYLAMINO BRIDGED HETEROCYCLIC COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2023-11-22 | — | — | EP | claimed |
| CN-116970580-A | Short-chain dehydrogenase mutant derived from Raffina and application of short-chain dehydrogenase mutant in catalyzing aryl ketone to prepare chiral alcohol | 浙江工业大学 | 2023-10-31 | — | — | CN | claimed |
| EP-2029614-B1 | COLD MENTHOL RECEPTOR-1 ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-23 | — | — | EP | claimed |
| US-20110003808-A1 | OCTAHYDROQUINOLIZINES FOR ANTIDIABETIC TREATMENT | 55PHARMA DRUG DISCOVERY & DEVELOPMENT AG (AT) | 2011-01-06 | — | — | US | claimed |
| EP-2222673-A1 | OCTAHYDROQUINOLI ZINES FOR ANTIDIABETIC TREATMENT | 55pharma Drug Discovery & Development AG (AT) | 2010-09-01 | — | — | EP | claimed |
| US-7741479-B2 | Urea inhibitors of MAP kinases | LOCUS PHARMACEUTICALS, INC. (US) | 2010-06-22 | — | — | US | claimed |
| WO-2009076693-A1 | OCTAHYDROQUINOLI ZINES FOR ANTIDIABETIC TREATMENT | 55PHARMA DRUG DISCOVERY & DEVELOPMENT AG (AT) | 2009-06-25 | — | — | WO | claimed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| EP-1828169-A2 | UREA INHIBITORS OF MAP KINASES | Locus Pharmaceuticals, Inc. (US) | 2007-09-05 | — | — | EP | claimed |
| US-20060167247-A1 | Urea inhibitors of MAP kinases | LOCUS PHARMACEUTICALS, INC. | 2006-07-27 | — | — | US | claimed |
| WO-2006062982-A2 | UREA INHIBITORS OF MAP KINASES | LOCUS PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | claimed |