Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20405134 | 0.85 | AURKA (0.38) | AURKAPARP1CHEK1FEN1KMT2A | |
| SCHEMBL7965933 | 0.81 | KMT2A (0.45) | AURKAPARP1FEN1KMT2AMEN1 | |
| SCHEMBL12900321 | 0.74 | HPGD (0.39) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL24354877 | 0.74 | AURKA (0.42) | AURKAPARP1CHEK1FEN1KMT2A | |
| SCHEMBL13451893 | 0.73 | ACHE (0.40) | AURKAPARP1FEN1MAPTALDH1A1 | |
| SCHEMBL24354886 | 0.72 | AURKA (0.40) | AURKAPARP1CHEK1FEN1KMT2A | |
| SCHEMBL1779138 | 0.72 | ADORA2A (0.44) | AURKAPARP1CHEK1KMT2AMEN1 | |
| SCHEMBL1779139 | 0.72 | ADORA2A (0.44) | AURKAPARP1CHEK1KMT2AMEN1 | |
| SCHEMBL17178085 | 0.71 | AHR (0.42) | CHEK1KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL18157770 | 0.71 | ALK (0.51) | AURKAPARP1CHEK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10777749-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2020-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10777749-B2 | Organic electroluminescent materials and devices | OCIAD2, OCIAD1, JUND | AURKA 2487/4885PARP1 1358/4885CHEK1 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.