Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18897171 | 0.91 | FGFR4 (0.46) | FGFR4 | |
| SCHEMBL18897164 | 0.87 | FGFR4 (0.56) | FGFR4 | |
| SCHEMBL18897273 | 0.86 | FGFR4 (0.73) | FGFR4 | |
| SCHEMBL18897178 | 0.85 | FGFR4 (0.53) | FGFR4 | |
| SCHEMBL19800952 | 0.84 | FGFR4 (0.77) | FGFR4 | |
| SCHEMBL21166528 | 0.84 | FGFR4 (0.77) | FGFR4 | |
| SCHEMBL24224985 | 0.81 | FGFR4 (0.68) | FGFR4 | |
| SCHEMBL23652929 | 0.80 | FGFR4 (0.68) | FGFR4 | |
| SCHEMBL23653129 | 0.80 | FGFR4 (0.69) | FGFR4 | |
| SCHEMBL22420093 | 0.79 | FGFR4 (0.74) | FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10774052-B2 | Heteroaryl compounds and uses thereof | CELGENE CAR LLC (BM) | 2020-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10774052-B2 | Heteroaryl compounds and uses thereof | ABCG2, CYP3A43, CYP3A5 | FGFR4 2623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.