Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307512 | 0.82 | MAPT (0.42) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL12516825 | 0.78 | MAPT (0.42) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL31273011 | 0.78 | MAPT (0.42) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL18180889 | 0.78 | MAPT (0.35) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL10307520 | 0.78 | MAPT (0.35) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL12459711 | 0.69 | MAPT (0.41) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL22305507 | 0.67 | PKM (0.41) | MAPTMEN1ALDH1A1KMT2ANPC1 | |
| Grossheimin SCHEMBL1711489 | 0.64 | MAPT (0.34) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| Grossheimin SCHEMBL1711493 | 0.64 | MAPT (0.34) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL10307519 | 0.63 | MAPT (0.43) | MAPTMEN1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661266-B1 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ANJI PHARMA (US) LLC (US) | 2020-09-16 | — | — | EP | disclosed |