Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.60 |
| ▸ | LIPE | Q05469 | 7/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24244600 | 0.94 | PDE4B (0.58) | PDE4BLIPEPLA2G10PDE1APDE1B | |
| SCHEMBL23512882 | 0.91 | PDE4B (0.61) | PDE4BLIPEPLA2G10 | |
| SCHEMBL22423380 | 0.89 | PDE4B (0.63) | PDE4BLIPE | |
| SCHEMBL11993071 | 0.84 | PDE4B (0.39) | PDE4BLIPE | |
| SCHEMBL22423325 | 0.82 | PDE4B (0.40) | PDE4BLIPEPDE1APDE1BPDE7A | |
| SCHEMBL25590231 | 0.78 | LIPE (0.35) | PDE4BLIPE | |
| SCHEMBL11993097 | 0.77 | NNMT (0.43) | PDE4BLIPEPLA2G10 | |
| SCHEMBL2529401 | 0.77 | PDE4B (0.40) | PDE4BLIPE | |
| SCHEMBL2529391 | 0.76 | PDE4B (0.41) | PDE4BLIPE | |
| SCHEMBL2527658 | 0.76 | F10 (0.40) | PDE4BLIPEPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708568-A1 | COMPOUND CAPABLE OF INHIBITING PHOSPHODIESTERASE 4, PREPARATION METHOD, AND MEDICAL USE THEREOF | Hefei Industrial Pharmaceutical Institute Co., Ltd (CN) | 2020-09-16 | — | — | EP | disclosed |