Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PRLHR | P49683 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24275973 | 0.90 | P2RX7 (0.39) | P2RX7PGRPRLHR | |
| SCHEMBL22410812 | 0.86 | P2RX7 (0.37) | P2RX7ABL1PGR | |
| SCHEMBL22410811 | 0.86 | P2RX7 (0.37) | P2RX7ABL1PGR | |
| SCHEMBL22424211 | 0.85 | P2RX7 (0.36) | P2RX7ABL1 | |
| SCHEMBL22423976 | 0.85 | P2RX7 (0.36) | P2RX7ABL1 | |
| SCHEMBL22424125 | 0.85 | P2RX7 (0.36) | P2RX7ABL1PRLHR | |
| SCHEMBL22423962 | 0.85 | P2RX7 (0.36) | P2RX7ABL1PGRTACR2TACR1 | |
| SCHEMBL25051697 | 0.85 | P2RX7 (0.36) | P2RX7ABL1PRLHR | |
| SCHEMBL22423985 | 0.85 | P2RX7 (0.36) | P2RX7HPGDABL1PGRPRLHR | |
| SCHEMBL22424304 | 0.85 | P2RX7 (0.36) | P2RX7ABL1PGRPRLHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |