Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3298689 | 0.89 | PARP1 (0.47) | GPR119PARP1TNKS2PARP2 | |
| SCHEMBL22410639 | 0.85 | GPR119 (0.46) | GPR119PARP1TNKS2PARP2GCK | |
| SCHEMBL22410777 | 0.82 | GPR119 (0.43) | GPR119PARP1TNKS2PARP2GCK | |
| SCHEMBL3303490 | 0.81 | PARP1 (0.41) | GPR119PARP1TNKS2PARP2 | |
| SCHEMBL22410755 | 0.80 | P2RX3 (0.45) | PARP1TNKS2PARP2 | |
| SCHEMBL22423970 | 0.75 | GPR119 (0.47) | GPR119 | |
| SCHEMBL13250459 | 0.75 | PARP1 (0.42) | GPR119PARP1TNKS2PARP2GCK | |
| SCHEMBL13250470 | 0.73 | PARP1 (0.46) | GPR119PARP1TNKS2PARP2GCK | |
| SCHEMBL29579602 | 0.73 | MAPT (0.48) | GPR119PARP1TNKS2PARP2 | |
| SCHEMBL3296988 | 0.72 | PARP1 (0.48) | GPR119PARP1TNKS2PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182990-A1 | FUSED RING PYRIMIDONE DERIVATIVES FOR USE IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2020-09-17 | — | — | WO | disclosed |