Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22425353 | 0.82 | CCR1 (0.39) | USP30KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22425584 | 0.78 | USP30 (0.34) | USP30 | |
| SCHEMBL21588488 | 0.77 | GRIN2D (0.36) | USP30ACACBKDM4EALDH1A1 | |
| SCHEMBL21154012 | 0.76 | PLD1 (0.38) | USP30KDM4ESMN1; SMN2 | |
| SCHEMBL22425500 | 0.74 | CHI3L1 (0.35) | ACACB | |
| SCHEMBL22425499 | 0.74 | LRRK2 (0.50) | — | |
| SCHEMBL22409840 | 0.74 | LRRK2 (0.50) | — | |
| SCHEMBL21999969 | 0.68 | CNR2 (0.35) | USP30SMN1; SMN2 | |
| SCHEMBL21154522 | 0.68 | CNR2 (0.35) | USP30SMN1; SMN2 | |
| SCHEMBL22000882 | 0.68 | CNR2 (0.35) | USP30SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020182666-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2020-09-17 | — | — | WO | disclosed |