Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22252393 | 0.91 | MALT1 (0.36) | MALT1HTR2CSLC6A4P2RX3 | |
| SCHEMBL22252388 | 0.84 | LMNA (0.36) | MALT1P2RX3 | |
| SCHEMBL31161633 | 0.80 | TYK2 (0.40) | MALT1P2RX3 | |
| SCHEMBL31161680 | 0.80 | TYK2 (0.40) | MALT1P2RX3 | |
| SCHEMBL16259910 | 0.78 | BRD9 (0.43) | MALT1BRD9 | |
| SCHEMBL22252334 | 0.77 | TYK2 (0.33) | MALT1 | |
| SCHEMBL22252471 | 0.77 | TYK2 (0.33) | MALT1 | |
| SCHEMBL22252611 | 0.77 | MALT1 (0.31) | MALT1 | |
| SCHEMBL22252368 | 0.77 | TYK2 (0.33) | MALT1 | |
| SCHEMBL22273062 | 0.77 | TYK2 (0.33) | MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020185755-A1 | TYK2 INHIBITORS AND USES THEREOF | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2020-09-17 | — | — | WO | disclosed |