Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22426257 | 1.00 | ALDH1A1 (0.71) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22426271 | 0.95 | ALDH1A1 (0.62) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22426267 | 0.95 | ALDH1A1 (0.62) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9634928 | 0.92 | SMN1; SMN2 (0.69) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22426264 | 0.92 | SMN1; SMN2 (0.69) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22426278 | 0.90 | ALDH1A1 (0.57) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22426277 | 0.90 | ALDH1A1 (0.57) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22446336 | 0.88 | SMN1; SMN2 (0.61) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22426239 | 0.88 | ALDH1A1 (0.61) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22426240 | 0.88 | ALDH1A1 (0.61) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840514-B2 | Catalysts and methods for enantioselective conjugate addition of amines to unsaturated electrophiles | NORTHWESTERN UNIVERSITY (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210002221-A1 | CATALYSTS AND METHODS FOR ENANTIOSELECIVE CONJUGATE ADDITION OF AMINES TO UNSATURATED ELECTROPHILES | NORTHWESTERN UNIVERSITY | 2021-01-07 | — | — | US | disclosed |
| US-10781172-B2 | Catalysts and methods for enantioselective conjugate additions of amines to unsaturated electrophiles | NORTHWESTERN UNIVERSITY (US) | 2020-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11840514-B2 | Catalysts and methods for enantioselective conjugate addition of amines to unsaturated electrophiles | AADAC, COASY, PAICS | ALDH1A1 142/4885POLB 828/4885SMN1; SMN2 934/4885 |
| US-10781172-B2 | Catalysts and methods for enantioselective conjugate additions of amines to unsaturated electrophiles | AADAC, COASY, PAICS | ALDH1A1 126/4885POLB 847/4885SMN1; SMN2 999/4885 |
| US-20210002221-A1 | CATALYSTS AND METHODS FOR ENANTIOSELECIVE CONJUGATE ADDITION OF AMINES TO UNSATURATED ELECTROPHILES | COASY, AADAC, AOC1 | ALDH1A1 97/4885POLB 885/4885SMN1; SMN2 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.