SCHEMBL224317

SCHEMBL224317

Nc1cccc2ccc(SSc3ccc4cccc(N)c4c3)cc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
HSD17B10 Q99714 6/20 0.52
CYP3A4 P08684 4/20 0.52
TSHR P16473 4/20 0.52
HPGD P15428 3/20 0.52
KEAP1 Q14145 1/20 0.52
F2 P00734 1/20 0.52
PLG P00747 1/20 0.52
PLAU P00749 1/20 0.52
PLAT P00750 1/20 0.52
KLK1 P06870 1/20 0.52
PRSS1 P07477 1/20 0.52
TDP1 Q9NUW8 4/20 0.49
KMT2A Q03164 4/20 0.49
KDM4E B2RXH2 3/20 0.49
POLB P06746 3/20 0.49
MEN1 O00255 3/20 0.49
MAPT P10636 3/20 0.49
TDP2 O95551 2/20 0.49
CASP6 P55212 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL222833 0.85 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP3A4TSHRHPGD
SCHEMBL14587264 0.77 F2 (0.46) ALDH1A1HSD17B10CYP3A4TSHRHPGD
SCHEMBL7835630 0.77 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP3A4TSHRHPGD
SCHEMBL729842 0.76 CTDSP1 (0.63) ALDH1A1HSD17B10CYP3A4TSHRHPGD
SCHEMBL29498396 0.76 CTDSP1 (0.63) ALDH1A1HSD17B10CYP3A4TSHRHPGD
SCHEMBL29405526 0.76 CTDSP1 (0.63) ALDH1A1HSD17B10CYP3A4TSHRHPGD
SCHEMBL8604165 0.74 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP3A4TSHRHPGD
SCHEMBL29351158 0.74 ALDH1A1 (0.62) ALDH1A1HSD17B10CYP3A4TSHRHPGD
SCHEMBL5545202 0.74 ALDH1A1 (0.62) ALDH1A1HSD17B10CYP3A4TSHRHPGD
SCHEMBL19071142 0.72 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP3A4TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 559 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6998444-B2 Vulcanization accelerator in crosslinked cis-polybutadiene core for increase compression and low coefficient of restitution, without causing any isomerism; use small amounts of crosslinker zinc diacrylate ACUSHNET COMPANY (US) 2006-02-14 US claimed
US-20050256274-A1 Golf ball core compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-6960629-B2 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY (US) 2005-11-01 US claimed
US-20040230006-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-18 US claimed
US-20040230005-A1 Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions ACUSHNET COMPANY 2004-11-18 US claimed
US-10933285-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2021-03-02 US disclosed
US-20200197757-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-06-25 US disclosed
US-10596419-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2020-03-24 US disclosed
US-20200086174-A1 A GOLF BALL COMPRISING A VERY-LOW MELT FLOW INNER COVER LAYER COMPOSITION JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2020-03-19 US disclosed
US-20200047033-A1 MULTI-LAYER CORE GOLF BALL ACUSHNET COMPANY (US) 2020-02-13 US disclosed
US-10478674-B2 Golf ball comprising a very-low melt flow inner cover layer composition ACUSHNET COMPANY (US) 2019-11-19 US disclosed
US-10478675-B2 Multi-layer core golf ball ACUSHNET COMPANY (US) 2019-11-19 US disclosed
US-20020006837-A1 Wound golf ball having cast polyurethane cover ACUSHNET COMPANY 2002-01-17 US disclosed
WO-2000038794-A9 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET CO (US) 2001-11-01 WO disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed
US-6291592-B1 HARDNESS, STIFFNESS ACUSHNET COMPANY 2001-09-18 US disclosed
WO-2000038794-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AN ORGANOSULFUR CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038793-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING ELEMENTAL CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
WO-2000038795-A1 LOW COMPRESSION, RESILIENT GOLF BALLS INCLUDING AROMATIC CATALYST AND METHOD FOR MAKING SAME ACUSHNET COMPANY (US) 2000-07-06 WO disclosed
US-5816939-A AGING RESISTANCE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 1998-10-06 US disclosed