Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222833 | 0.88 | ALDH1A1 (0.54) | ALDH1A1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL223523 | 0.82 | ALDH1A1 (0.65) | ALDH1A1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL224317 | 0.74 | ALDH1A1 (0.52) | ALDH1A1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL225183 | 0.72 | HSD17B10 (0.41) | ALDH1A1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL224693 | 0.71 | PLAU (0.57) | ALDH1A1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL223790 | 0.70 | HSD17B10 (0.50) | ALDH1A1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL225136 | 0.69 | CYP3A4 (0.50) | ALDH1A1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL29404930 | 0.68 | PLAU (0.63) | ALDH1A1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL29498391 | 0.68 | PLAU (0.63) | ALDH1A1CYP3A4HPGDHSD17B10TSHR | |
| SCHEMBL731002 | 0.68 | PLAU (0.63) | ALDH1A1CYP3A4HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5816939-A | AGING RESISTANCE | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 1998-10-06 | — | — | US | disclosed |