Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354534 | 0.96 | KMT2A (0.44) | KMT2ARAD52RXFP1HTR2CHTR2B | |
| SCHEMBL60540 | 0.73 | HTR2C (0.69) | KMT2ARAD52RXFP1HTR2CHTR2B | |
| SCHEMBL11223239 | 0.73 | KMT2A (0.59) | KMT2ARAD52RXFP1HTR2CHTR2B | |
| SCHEMBL13989159 | 0.73 | KMT2A (0.53) | KMT2ARAD52RXFP1HTR2CHTR2B | |
| Bromide SCHEMBL8863742 | 0.71 | HTR2C (0.67) | KMT2ARAD52RXFP1HTR2CHTR2B | |
| SCHEMBL2837125 | 0.71 | KMT2A (0.47) | KMT2ARAD52RXFP1HTR2CHTR2B | |
| SCHEMBL6990481 | 0.71 | CYP11B1 (0.48) | KMT2AL3MBTL1 | |
| SCHEMBL6996752 | 0.70 | KMT2A (0.40) | KMT2ARAD52RXFP1HTR2CHTR2B | |
| SCHEMBL6992548 | 0.70 | NPC1 (0.50) | KMT2AMAPTTDP1GAALMNA | |
| SCHEMBL15267534 | 0.70 | KMT2A (0.50) | KMT2ARAD52RXFP1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268375-B1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2022-06-15 | — | — | EP | claimed |
| US-20220137262-A1 | OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS WITH REACTIVE SUBSTITUENTS | JOHNSON & JOHNSON VISION CARE (US) | 2022-05-05 | — | — | US | claimed |
| EP-3071576-B9 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-12-22 | — | — | EP | claimed |
| EP-3645540-B1 | SILOLE AND GERMOLE FUSED RING PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL LTD (IE) | 2021-11-03 | — | — | EP | claimed |
| EP-3071576-B1 | PHOTOCHROMIC INDENO-FUSED RING PYRAN COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2021-08-18 | — | — | EP | claimed |
| CN-105199708-B | Photochromic compounds | 光学转变公司 | 2020-10-27 | — | — | CN | claimed |
| US-20200172798-A1 | Silole and Germole Fused Ring Photochromic Compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2020-06-04 | — | — | US | claimed |
| EP-3645540-A1 | SILOLE AND GERMOLE FUSED RING PHOTOCHROMIC COMPOUNDS | Transitions Optical, Ltd. (IE) | 2020-05-06 | — | — | EP | claimed |
| EP-3621958-A1 | PHOTOCHROMIC INDENO FUSED PHENANTHRENOPYRAN COMPOUNDS | Transitions Optical, Ltd. (IE) | 2020-03-18 | — | — | EP | claimed |
| CN-110799514-A | Silole and germacyclopentadiene fused ring photochromic compounds | 光学转变有限公司 | 2020-02-14 | — | — | CN | claimed |
| US-4365016-A | ELECTROGRAPHY | EASTMAN KODAK COMPANY (US) | 1982-12-21 | — | — | US | claimed |
| US-4365017-A | ELECTROGRAPHY | EASTMAN KODAK COMPANY (US) | 1982-12-21 | — | — | US | claimed |
| US-4363503-A | FOR PRESSURE SENSITIVE CARBONLESS DUPLICATING AND THERMAL MARKING SYSTEMS | STERLING DRUG INC. (US) | 1982-12-14 | — | — | US | claimed |
| EP-0061128-A1 | Pyridine compounds, process for their preparation and systems containing them | STERLING DRUG INC. (US) | 1982-09-29 | — | — | EP | claimed |
| US-4255577-A | Process and intermediates for preparing 3-[4-(disubstituted-amino)phenyl] or | STERLING DRUG INC. (US) | 1981-03-10 | — | — | US | claimed |
| US-4200313-A | Carbonless duplicating systems | STERLING DRUG INC. (US) | 1980-04-29 | — | — | US | claimed |
| US-4175956-A | Electrophotosensitive materials for migration imaging processes | EASTMAN KODAK COMPANY (US) | 1979-11-27 | — | — | US | claimed |
| US-4168378-A | THERMOGRAPHY, LEUCO DYES | STERLING DRUG INC. (US) | 1979-09-18 | — | — | US | claimed |
| US-4146707-A | PHOTOELECTROPHORESIS | EASTMAN KODAK COMPANY (US) | 1979-03-27 | — | — | US | claimed |
| US-4119776-A | Vinyl phthalide color formers | NCR CORPORATION (US) | 1978-10-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172798-A1 | Silole and Germole Fused Ring Photochromic Compounds | CCNB2, SKP2, CCNB1 | KMT2A 888/4885RAD52 640/4885RXFP1 3743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.