SCHEMBL224346

SCHEMBL224346

Cc1cc(N)ccc1C(c1ccc(N)cc1)c1ccc(N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
PDE10A Q9Y233 1/20 0.43
CASP1 P29466 3/20 0.41
CYP3A4 P08684 2/20 0.39
TSHR P16473 2/20 0.39
MAPT P10636 5/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
LMNA P02545 3/20 0.38
THRB P10828 2/20 0.38
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALOX15 P16050 1/20 0.38
ACHE P22303 1/20 0.37
GAA P10253 1/20 0.35
NR4A1 P22736 1/20 0.35
PTK2B Q14289 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL8976105 0.98 ALDH1A1 (0.46) ALDH1A1PDE10ACASP1CYP3A4TSHR
SCHEMBL22043958 0.88 ACHE (0.44) ALDH1A1CASP1CYP3A4MAPTLMNA
SCHEMBL22044373 0.88 ALDH1A1 (0.45) ALDH1A1PDE10ACASP1CYP3A4TSHR
SCHEMBL31409211 0.88 ALDH1A1 (0.45) ALDH1A1PDE10ACASP1CYP3A4TSHR
SCHEMBL3903539 0.87 ALDH1A1 (0.56) ALDH1A1PDE10ACASP1CYP3A4TSHR
SCHEMBL5667003 0.85 CYP3A4 (0.42) ALDH1A1PDE10ACASP1CYP3A4TSHR
SCHEMBL22044344 0.84 ALDH1A1 (0.45) ALDH1A1PDE10ACASP1CYP3A4TSHR
SCHEMBL22050368 0.83 ALDH1A1 (0.43) ALDH1A1PDE10ACASP1CYP3A4TSHR
SCHEMBL6252567 0.82 ALDH1A1 (0.48) ALDH1A1PDE10ACASP1CYP3A4TSHR
SCHEMBL22051088 0.82 HSD17B10 (0.45) ALDH1A1PDE10ACASP1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4258123-A UNSATURATED COMPOUND, HALOGENATED TRIAZINE, UNSATURATED KETONE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US claimed
US-20120000385-A1 LITHOGRAPHIC PRINTING PLATE MATERIAL AND LITHOGRAPHIC PRINTING PLATE KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2012-01-05 US disclosed
US-20090075201-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL, AND CYCLIC UREIDE MOIETY-CONTAINING PHENOLIC RESIN AND ITS SYNTHETIC PROCESS KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-03-19 US disclosed
EP-1498281-B1 Printing method using printing plate KONICA MINOLTA MED & GRAPHIC (JP) 2008-12-03 EP disclosed
US-20080274425-A1 Multilayeer; aluminum support with fluoroalkyl acrylic group containing polymer; alkali soluble resin and an acid generator KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-11-06 US disclosed
EP-1220041-B1 Method for preparing lithographic printing plate FUJIFILM CORP (JP) 2008-09-17 EP disclosed
US-20080206677-A1 Planographic printing plate material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-08-28 US disclosed
EP-1188580-B1 Aluminum support for planographic printing plate, process for its production, and planographic printing master place FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-20080182202-A1 Planographic printing plate material and resin used therein KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-31 US disclosed
US-20080160445-A1 Planographic printing plate material, and method of preparing planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
EP-0118766-B1 LIGHT-SENSITIVE COMPOSITION KONICA CORPORATION (JP) 1989-01-04 EP disclosed
US-4772534-A PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1988-09-20 US disclosed
US-4769308-A Dry presensitized plate with photosensitive layer containing organotin FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed
US-4701399-A Photosensitive composition with 2-halomethyl-5-substituted-1,3,4-oxadiazole FUJI PHOTO FILM CO., LTD. (JP) 1987-10-20 US disclosed
EP-0118766-A2 Light-sensitive composition KONICA CORPORATION (JP) 1984-09-19 EP disclosed
EP-0115156-A2 Light sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1984-08-08 EP disclosed
US-4399210-A O-NAPHTHOQUINONEDIAZIDE AND A DISCOLORING AGENT FUJI PHOTO FILM COMPANY LTD. (JP) 1983-08-16 US disclosed
US-4279982-A PRINTOUTS; OXADIAZOLE PHOTOINITIATORS FUJI PHOTO FILM CO., LTD. (JP) 1981-07-21 US disclosed
US-4258123-A UNSATURATED COMPOUND, HALOGENATED TRIAZINE, UNSATURATED KETONE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4232106-A Photosensitive compositions containing 2-halomethyl-5-vinyl-1,3,4-oxadiazoles as free radical progenitors FUJI PHOTO FILM CO., LTD. (JP) 1980-11-04 US disclosed